ENSG00000134873


Homo sapiens

Features
Gene ID: ENSG00000134873
  
Biological name :CLDN10
  
Synonyms : claudin 10 / CLDN10 / P78369
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 13
Strand: 1
Band: q32.1
Gene start: 95433604
Gene end: 95579759
  
Corresponding Affymetrix probe sets: 1556687_a_at (Human Genome U133 Plus 2.0 Array)   205328_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000299339
Ensembl peptide - ENSP00000366051
Ensembl peptide - ENSP00000366069
NCBI entrez gene - 9071     See in Manteia.
OMIM - 617579
RefSeq - XM_017020844
RefSeq - NM_001160100
RefSeq - NM_006984
RefSeq - NM_182848
RefSeq - XM_011521134
RefSeq - XM_017020843
RefSeq Peptide - NP_001153572
RefSeq Peptide - NP_008915
RefSeq Peptide - NP_878268
swissprot - P78369
swissprot - Q5W075
Ensembl - ENSG00000134873
  
Related genetic diseases (OMIM): 617671 - HELIX syndrome, 617671
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cldn10aENSDARG00000058937Danio rerio
 cldn10bENSDARG00000104528Danio rerio
 CLDN10ENSGALG00000019114Gallus gallus
 Cldn10ENSMUSG00000022132Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CLDN15 / P56746 / claudin 15ENSG0000010640443
CLDN17 / P56750 / claudin 17ENSG0000015628232
CLDN18 / P56856 / claudin 18ENSG0000006640532
CLDN20 / P56880 / claudin 20ENSG0000017121728
A6NM45 / CLDN24 / claudin 24ENSG0000018575826
CLDN22 / Q8N7P3 / claudin 22ENSG0000017730025
C9JDP6 / CLDN25 / claudin 25ENSG0000022860720


Protein motifs (from Interpro)
Interpro ID Name
 IPR003554  Claudin-10
 IPR004031  PMP-22/EMP/MP20/Claudin superfamily
 IPR006187  Claudin
 IPR017974  Claudin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0007155 cell adhesion TAS
 biological_processGO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules ISS
 biological_processGO:0043269 regulation of ion transport IMP
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005923 bicellular tight junction IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 molecular_functionGO:0005198 structural molecule activity IEA
 molecular_functionGO:0042802 identical protein binding ISS


Pathways (from Reactome)
Pathway description
Tight junction interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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