ENSG00000135916


Homo sapiens

Features
Gene ID: ENSG00000135916
  
Biological name :ITM2C
  
Synonyms : integral membrane protein 2C / ITM2C / Q9NQX7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: q37.1
Gene start: 230864639
Gene end: 230879248
  
Corresponding Affymetrix probe sets: 221004_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000387242
Ensembl peptide - ENSP00000390655
Ensembl peptide - ENSP00000480137
Ensembl peptide - ENSP00000444899
Ensembl peptide - ENSP00000440295
Ensembl peptide - ENSP00000403257
Ensembl peptide - ENSP00000322100
Ensembl peptide - ENSP00000322730
Ensembl peptide - ENSP00000335121
NCBI entrez gene - 81618     See in Manteia.
OMIM - 609554
RefSeq - NM_030926
RefSeq - NM_001012514
RefSeq - NM_001012516
RefSeq - NM_001287240
RefSeq - NM_001287241
RefSeq Peptide - NP_001012532
RefSeq Peptide - NP_001012534
RefSeq Peptide - NP_001274169
RefSeq Peptide - NP_001274170
RefSeq Peptide - NP_112188
swissprot - Q9NQX7
swissprot - C9JG41
swissprot - B8ZZM6
swissprot - A0A024R466
swissprot - F5H4I5
swissprot - Q96JS4
swissprot - E7EUS6
Ensembl - ENSG00000135916
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 itm2caENSDARG00000043448Danio rerio
 itm2cbENSDARG00000039650Danio rerio
 ITM2CENSGALG00000036111Gallus gallus
 Itm2cENSMUSG00000026223Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ITM2B / Q9Y287 / integral membrane protein 2BENSG0000013615642
ITM2A / O43736 / integral membrane protein 2AENSG0000007859635


Protein motifs (from Interpro)
Interpro ID Name
 IPR007084  BRICHOS domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010977 negative regulation of neuron projection development IDA
 biological_processGO:0030182 neuron differentiation ISS
 biological_processGO:0042985 negative regulation of amyloid precursor protein biosynthetic process IBA
 biological_processGO:2001238 positive regulation of extrinsic apoptotic signaling pathway IEA
 cellular_componentGO:0005764 lysosome ISS
 cellular_componentGO:0005765 lysosomal membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0001540 amyloid-beta binding IPI
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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