ENSG00000136448


Homo sapiens

Features
Gene ID: ENSG00000136448
  
Biological name :NMT1
  
Synonyms : NMT1 / N-myristoyltransferase 1 / P30419
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q21.31
Gene start: 45051610
Gene end: 45109016
  
Corresponding Affymetrix probe sets: 201157_s_at (Human Genome U133 Plus 2.0 Array)   201158_at (Human Genome U133 Plus 2.0 Array)   201159_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000466827
Ensembl peptide - ENSP00000468424
Ensembl peptide - ENSP00000258960
Ensembl peptide - ENSP00000439263
Ensembl peptide - ENSP00000466777
NCBI entrez gene - 4836     See in Manteia.
OMIM - 160993
RefSeq - NM_021079
RefSeq - XM_011524858
RefSeq Peptide - NP_066565
swissprot - K7EN82
swissprot - B7Z8J4
swissprot - P30419
swissprot - K7EN42
Ensembl - ENSG00000136448
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nmt1aENSDARG00000052966Danio rerio
 NMT1ENSGALG00000000857Gallus gallus
 Nmt1ENSMUSG00000020936Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NMT2 / O60551 / N-myristoyltransferase 2ENSG0000015246573


Protein motifs (from Interpro)
Interpro ID Name
 IPR000903  Myristoyl-CoA:protein N-myristoyltransferase
 IPR016181  Acyl-CoA N-acyltransferase
 IPR022676  Myristoyl-CoA:protein N-myristoyltransferase, N-terminal
 IPR022677  Myristoyl-CoA:protein N-myristoyltransferase, C-terminal
 IPR022678  Myristoyl-CoA:protein N-myristoyltransferase, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0006499 N-terminal protein myristoylation TAS
 biological_processGO:0018008 N-terminal peptidyl-glycine N-myristoylation IDA
 biological_processGO:0022400 regulation of rhodopsin mediated signaling pathway TAS
 biological_processGO:0042180 cellular ketone metabolic process IDA
 biological_processGO:1900740 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0019898 extrinsic component of membrane IDA
 molecular_functionGO:0004379 glycylpeptide N-tetradecanoyltransferase activity TAS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016746 transferase activity, transferring acyl groups IEA
 molecular_functionGO:0019107 myristoyltransferase activity TAS


Pathways (from Reactome)
Pathway description
Late Phase of HIV Life Cycle
Inactivation, recovery and regulation of the phototransduction cascade
Activation, myristolyation of BID and translocation to mitochondria


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000114349 GNAT1 / P11488 / G protein subunit alpha transducin 1  / reaction
 ENSG00000015475 BID / P55957 / BH3 interacting domain death agonist  / reaction






 

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