ENSG00000136699


Homo sapiens

Features
Gene ID: ENSG00000136699
  
Biological name :SMPD4
  
Synonyms : Q9NXE4 / SMPD4 / sphingomyelin phosphodiesterase 4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: q21.1
Gene start: 130151392
Gene end: 130182750
  
Corresponding Affymetrix probe sets: 207856_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000406458
Ensembl peptide - ENSP00000406325
Ensembl peptide - ENSP00000407591
Ensembl peptide - ENSP00000416208
Ensembl peptide - ENSP00000259217
Ensembl peptide - ENSP00000386531
Ensembl peptide - ENSP00000393791
Ensembl peptide - ENSP00000397078
Ensembl peptide - ENSP00000397278
Ensembl peptide - ENSP00000401648
Ensembl peptide - ENSP00000403002
Ensembl peptide - ENSP00000403915
Ensembl peptide - ENSP00000405187
Ensembl peptide - ENSP00000405363
NCBI entrez gene - 55627     See in Manteia.
OMIM - 610457
RefSeq - XM_017004449
RefSeq - NM_001171083
RefSeq - NM_017751
RefSeq - NM_017951
RefSeq - XM_011511443
RefSeq - XM_011511444
RefSeq - XM_011511445
RefSeq - XM_017004448
RefSeq Peptide - NP_001164554
RefSeq Peptide - NP_060221
RefSeq Peptide - NP_060421
swissprot - H7C2J2
swissprot - Q9NXE4
swissprot - B1PBA3
swissprot - C9J647
swissprot - F2Z2I0
swissprot - F2Z2W5
swissprot - F8WEQ5
swissprot - F8WF03
swissprot - H7BXF4
swissprot - H7C1Q6
swissprot - H7C0W5
swissprot - H7C235
swissprot - H7C2E2
Ensembl - ENSG00000136699
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 smpd4ENSDARG00000020730Danio rerio
 ENSGALG00000006455Gallus gallus
 Smpd4ENSMUSG00000005899Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR024129  Sphingomyelin phosphodiesterase 4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006685 sphingomyelin catabolic process IDA
 biological_processGO:0006687 glycosphingolipid metabolic process TAS
 biological_processGO:0046475 glycerophospholipid catabolic process IDA
 biological_processGO:0046513 ceramide biosynthetic process IDA
 biological_processGO:0071356 cellular response to tumor necrosis factor IDA
 cellular_componentGO:0000139 Golgi membrane IEA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005794 Golgi apparatus IDA
 cellular_componentGO:0005802 trans-Golgi network IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004767 sphingomyelin phosphodiesterase activity TAS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0050290 sphingomyelin phosphodiesterase D activity IDA


Pathways (from Reactome)
Pathway description
Glycosphingolipid metabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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