ENSG00000136824


Homo sapiens

Features
Gene ID: ENSG00000136824
  
Biological name :SMC2
  
Synonyms : O95347 / SMC2 / structural maintenance of chromosomes 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: 1
Band: q31.1
Gene start: 104094260
Gene end: 104141417
  
Corresponding Affymetrix probe sets: 204240_s_at (Human Genome U133 Plus 2.0 Array)   213253_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000431534
Ensembl peptide - ENSP00000363919
Ensembl peptide - ENSP00000363925
Ensembl peptide - ENSP00000414999
Ensembl peptide - ENSP00000286398
NCBI entrez gene - 10592     See in Manteia.
OMIM - 605576
RefSeq - XM_017014212
RefSeq - XM_011518152
RefSeq - XM_011518153
RefSeq - XM_017014206
RefSeq - XM_017014207
RefSeq - XM_017014208
RefSeq - XM_017014209
RefSeq - XM_017014210
RefSeq - XM_017014211
RefSeq - NM_001042550
RefSeq - NM_001042551
RefSeq - NM_001265602
RefSeq - NM_006444
RefSeq - XM_006716933
RefSeq - XM_011518148
RefSeq - XM_011518149
RefSeq - XM_011518150
RefSeq - XM_011518151
RefSeq Peptide - NP_006435
RefSeq Peptide - NP_001036015
RefSeq Peptide - NP_001036016
RefSeq Peptide - NP_001252531
swissprot - A0A024R158
swissprot - O95347
swissprot - Q5T821
swissprot - A0A0C4DGE5
Ensembl - ENSG00000136824
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 smc2ENSDARG00000017744Danio rerio
 SMC2ENSGALG00000015691Gallus gallus
 Smc2ENSMUSG00000028312Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003395  RecF/RecN/SMC, N-terminal
 IPR010935  SMCs flexible hinge
 IPR024704  Structural maintenance of chromosomes protein
 IPR027120  Smc2, ATP-binding cassette domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR036277  SMCs flexible hinge superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007076 mitotic chromosome condensation TAS
 biological_processGO:0010032 meiotic chromosome condensation IEA
 biological_processGO:0030261 chromosome condensation IEA
 biological_processGO:0045132 meiotic chromosome segregation IEA
 biological_processGO:0051276 chromosome organization IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0051383 kinetochore organization IEA
 cellular_componentGO:0000228 nuclear chromosome IDA
 cellular_componentGO:0000793 condensed chromosome IDA
 cellular_componentGO:0000796 condensin complex IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0046982 protein heterodimerization activity IPI


Pathways (from Reactome)
Pathway description
Condensation of Prophase Chromosomes
Condensation of Prometaphase Chromosomes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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