ENSG00000137171


Homo sapiens

Features
Gene ID: ENSG00000137171
  
Biological name :KLC4
  
Synonyms : kinesin light chain 4 / KLC4 / Q9NSK0
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: p21.1
Gene start: 43040777
Gene end: 43075099
  
Corresponding Affymetrix probe sets: 1553675_at (Human Genome U133 Plus 2.0 Array)   225596_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000418031
Ensembl peptide - ENSP00000420144
Ensembl peptide - ENSP00000419784
Ensembl peptide - ENSP00000419634
Ensembl peptide - ENSP00000419102
Ensembl peptide - ENSP00000418759
Ensembl peptide - ENSP00000418546
Ensembl peptide - ENSP00000259708
Ensembl peptide - ENSP00000340221
Ensembl peptide - ENSP00000377620
Ensembl peptide - ENSP00000395806
Ensembl peptide - ENSP00000410358
Ensembl peptide - ENSP00000417620
Ensembl peptide - ENSP00000417652
NCBI entrez gene - 89953     See in Manteia.
RefSeq - XM_017011457
RefSeq - NM_001289034
RefSeq - NM_001289035
RefSeq - NM_138343
RefSeq - NM_201521
RefSeq - NM_201522
RefSeq - NM_201523
RefSeq - XM_011514989
RefSeq Peptide - NP_612352
RefSeq Peptide - NP_958929
RefSeq Peptide - NP_958930
RefSeq Peptide - NP_958931
RefSeq Peptide - NP_001275963
RefSeq Peptide - NP_001275964
swissprot - F8WCA4
swissprot - H7C4M1
swissprot - C9JZE5
swissprot - C9JXT5
swissprot - C9JQU1
swissprot - C9J8T5
swissprot - A0A024RCZ8
swissprot - Q9NSK0
swissprot - C9K0D5
Ensembl - ENSG00000137171
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 klc4ENSDARG00000086985Danio rerio
 KLC4ENSGALG00000030384Gallus gallus
 Klc4ENSMUSG00000003546Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KLC2 / Q9H0B6 / kinesin light chain 2ENSG0000017499668
KLC1 / Q07866 / kinesin light chain 1ENSG0000012621465
AL139300.1ENSG0000025650062
KLC3 / Q6P597 / kinesin light chain 3ENSG0000010489249
NPHP3 / Q7Z494 / nephrocystin 3ENSG0000011397126
NPHP3-ACAD11 / NPHP3-ACAD11 readthrough (NMD candidate)ENSG0000027481012


Protein motifs (from Interpro)
Interpro ID Name
 IPR002151  Kinesin light chain
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR015792  Kinesin light chain repeat
 IPR019734  Tetratricopeptide repeat
 IPR036388  Winged helix-like DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005871 kinesin complex IEA
 cellular_componentGO:0005874 microtubule IEA
 molecular_functionGO:0003777 microtubule motor activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
MHC class II antigen presentation
RHO GTPases activate KTN1
COPI-dependent Golgi-to-ER retrograde traffic
Kinesins


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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