ENSG00000137496


Homo sapiens

Features
Gene ID: ENSG00000137496
  
Biological name :IL18BP
  
Synonyms : IL18BP / interleukin 18 binding protein / O95998
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q13.4
Gene start: 71998541
Gene end: 72005715
  
Corresponding Affymetrix probe sets: 219323_s_at (Human Genome U133 Plus 2.0 Array)   222868_s_at (Human Genome U133 Plus 2.0 Array)   224283_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000434376
Ensembl peptide - ENSP00000384212
Ensembl peptide - ENSP00000434717
Ensembl peptide - ENSP00000480621
Ensembl peptide - ENSP00000434835
Ensembl peptide - ENSP00000260049
Ensembl peptide - ENSP00000338723
Ensembl peptide - ENSP00000343309
Ensembl peptide - ENSP00000377306
Ensembl peptide - ENSP00000377308
Ensembl peptide - ENSP00000377310
NCBI entrez gene - 10068     See in Manteia.
OMIM - 604113
RefSeq - XM_017017063
RefSeq - NM_001039659
RefSeq - NM_001039660
RefSeq - NM_001145055
RefSeq - NM_001145057
RefSeq - NM_005699
RefSeq - NM_173042
RefSeq - NM_173044
RefSeq - XM_017017059
RefSeq - XM_017017060
RefSeq - XM_017017061
RefSeq - XM_017017062
RefSeq Peptide - NP_001034748
RefSeq Peptide - NP_001138529
RefSeq Peptide - NP_005690
RefSeq Peptide - NP_766630
RefSeq Peptide - NP_766632
RefSeq Peptide - NP_001034749
RefSeq Peptide - NP_001138527
swissprot - A0A024R5M7
swissprot - A0A024R5I1
swissprot - G3V1C5
swissprot - A0A024R5G2
swissprot - O95998
Ensembl - ENSG00000137496
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Il18bpENSMUSG00000070427Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007110  Immunoglobulin-like domain
 IPR013783  Immunoglobulin-like fold
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0032496 response to lipopolysaccharide IEA
 biological_processGO:0035655 interleukin-18-mediated signaling pathway TAS
 biological_processGO:0042088 T-helper 1 type immune response IDA
 biological_processGO:0070301 cellular response to hydrogen peroxide IEA
 biological_processGO:0071345 cellular response to cytokine stimulus TAS
 biological_processGO:0071356 cellular response to tumor necrosis factor IEA
 biological_processGO:1900116 extracellular negative regulation of signal transduction IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0042007 interleukin-18 binding IDA
 molecular_functionGO:0048019 receptor antagonist activity TAS


Pathways (from Reactome)
Pathway description
Interleukin-37 signaling
Interleukin-18 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000125571 IL37 / Q9NZH6 / interleukin 37  / complex / reaction
 ENSG00000150782 IL18 / Q14116 / interleukin 18  / complex / reaction






 

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