ENSG00000137944


Homo sapiens

Features
Gene ID: ENSG00000137944
  
Biological name :KYAT3
  
Synonyms : KYAT3 / kynurenine aminotransferase 3 / Q6YP21
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: p22.2
Gene start: 88935773
Gene end: 88992953
  
Corresponding Affymetrix probe sets: 209472_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000359517
Ensembl peptide - ENSP00000359522
Ensembl peptide - ENSP00000260508
NCBI entrez gene - 56267     See in Manteia.
OMIM - 610656
RefSeq - NM_001008662
RefSeq - NM_001008661
RefSeq - NM_001349447
RefSeq - NM_001349448
RefSeq Peptide - NP_001008662
RefSeq Peptide - NP_001008661
RefSeq Peptide - NP_001336377
RefSeq Peptide - NP_001336376
swissprot - Q6YP21
swissprot - B4DW13
swissprot - A0A0A0MRN7
Ensembl - ENSG00000137944
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kyat3ENSDARG00000101791Danio rerio
 si:ch211-180m24.3ENSDARG00000102243Danio rerio
 si:ch73-97h19.2ENSDARG00000100818Danio rerio
 KYAT3ENSGALG00000006188Gallus gallus
 Kyat3ENSMUSG00000040213Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KYAT1 / Q16773 / kynurenine aminotransferase 1ENSG0000017109748
TAT / P17735 / tyrosine aminotransferaseENSG0000019865018


Protein motifs (from Interpro)
Interpro ID Name
 IPR004839  Aminotransferase, class I/classII
 IPR015421  Pyridoxal phosphate-dependent transferase, major domain
 IPR015422  Pyridoxal phosphate-dependent transferase domain 1
 IPR015424  Pyridoxal phosphate-dependent transferase
 IPR034612  Kynurenine--oxoglutarate transaminase 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006103 2-oxoglutarate metabolic process IEA
 biological_processGO:0006520 cellular amino acid metabolic process IEA
 biological_processGO:0009058 biosynthetic process IEA
 biological_processGO:0070189 kynurenine metabolic process IEA
 biological_processGO:0097052 L-kynurenine metabolic process IEA
 cellular_componentGO:0005739 mitochondrion IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0008483 transaminase activity IEA
 molecular_functionGO:0016212 kynurenine-oxoglutarate transaminase activity ISS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0030170 pyridoxal phosphate binding IEA
 molecular_functionGO:0036137 kynurenine aminotransferase activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0047315 kynurenine-glyoxylate transaminase activity ISS
 molecular_functionGO:0047804 cysteine-S-conjugate beta-lyase activity IEA


Pathways (from Reactome)
Pathway description
Tryptophan catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000137944 KYAT3 / Q6YP21 / kynurenine aminotransferase 3  / complex






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr