ENSG00000171097


Homo sapiens

Features
Gene ID: ENSG00000171097
  
Biological name :KYAT1
  
Synonyms : KYAT1 / kynurenine aminotransferase 1 / Q16773
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: q34.11
Gene start: 128832942
Gene end: 128882494
  
Corresponding Affymetrix probe sets: 1570650_at (Human Genome U133 Plus 2.0 Array)   1570651_at (Human Genome U133 Plus 2.0 Array)   206037_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000392354
Ensembl peptide - ENSP00000390377
Ensembl peptide - ENSP00000399415
Ensembl peptide - ENSP00000412402
Ensembl peptide - ENSP00000302227
Ensembl peptide - ENSP00000317342
NCBI entrez gene - 883     See in Manteia.
OMIM - 600547
RefSeq - XM_017015268
RefSeq - NM_001287390
RefSeq - NM_001352994
RefSeq - NM_001352995
RefSeq - NM_001352996
RefSeq - NM_004059
RefSeq - XM_006717311
RefSeq - XM_011519165
RefSeq - XM_011519167
RefSeq - XM_011519168
RefSeq - XM_011519169
RefSeq - XM_011519170
RefSeq - XM_017015260
RefSeq - XM_017015261
RefSeq - XM_017015262
RefSeq - XM_017015263
RefSeq - XM_017015264
RefSeq - XM_017015265
RefSeq - XM_017015266
RefSeq - XM_017015267
RefSeq - NM_001122671
RefSeq - NM_001122672
RefSeq Peptide - NP_001339924
RefSeq Peptide - NP_001339925
RefSeq Peptide - NP_004050
RefSeq Peptide - NP_001339918
RefSeq Peptide - NP_001339919
RefSeq Peptide - NP_001339920
RefSeq Peptide - NP_001339921
RefSeq Peptide - NP_001339922
RefSeq Peptide - NP_001339923
RefSeq Peptide - NP_001116143
RefSeq Peptide - NP_001116144
RefSeq Peptide - NP_001274319
RefSeq Peptide - NP_001339917
swissprot - Q16773
swissprot - Q5T276
swissprot - Q5T277
swissprot - Q5T278
swissprot - A8K563
swissprot - B7Z4W5
Ensembl - ENSG00000171097
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kyat1ENSDARG00000023645Danio rerio
 ENSGALG00000004604Gallus gallus
 Kyat1ENSMUSG00000039648Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KYAT3 / Q6YP21 / kynurenine aminotransferase 3ENSG0000013794442
TAT / P17735 / tyrosine aminotransferaseENSG0000019865017


Protein motifs (from Interpro)
Interpro ID Name
 IPR004839  Aminotransferase, class I/classII
 IPR015421  Pyridoxal phosphate-dependent transferase, major domain
 IPR015422  Pyridoxal phosphate-dependent transferase domain 1
 IPR015424  Pyridoxal phosphate-dependent transferase
 IPR034614  Kynurenine--oxoglutarate transaminase 1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006559 L-phenylalanine catabolic process TAS
 biological_processGO:0006569 tryptophan catabolic process TAS
 biological_processGO:0006575 cellular modified amino acid metabolic process IEA
 biological_processGO:0008652 cellular amino acid biosynthetic process TAS
 biological_processGO:0009058 biosynthetic process IEA
 biological_processGO:0070189 kynurenine metabolic process IEA
 biological_processGO:0097052 L-kynurenine metabolic process IEA
 biological_processGO:0097053 L-kynurenine catabolic process IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008483 transaminase activity IEA
 molecular_functionGO:0016212 kynurenine-oxoglutarate transaminase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0030170 pyridoxal phosphate binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IPI
 molecular_functionGO:0047312 L-phenylalanine:pyruvate aminotransferase activity EXP
 molecular_functionGO:0047316 glutamine-phenylpyruvate transaminase activity IEA
 molecular_functionGO:0047804 cysteine-S-conjugate beta-lyase activity IEA
 molecular_functionGO:0047945 L-glutamine:pyruvate aminotransferase activity EXP
 molecular_functionGO:0070548 L-glutamine aminotransferase activity IEA


Pathways (from Reactome)
Pathway description
Amino acid synthesis and interconversion (transamination)
Phenylalanine and tyrosine catabolism
Tryptophan catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000171097 KYAT1 / Q16773 / kynurenine aminotransferase 1  / complex






 

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