ENSG00000139410


Homo sapiens

Features
Gene ID: ENSG00000139410
  
Biological name :SDSL
  
Synonyms : Q96GA7 / SDSL / serine dehydratase like
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: 1
Band: q24.13
Gene start: 113422237
Gene end: 113438276
  
Corresponding Affymetrix probe sets: 228274_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000385790
Ensembl peptide - ENSP00000448950
Ensembl peptide - ENSP00000341117
Ensembl peptide - ENSP00000449136
Ensembl peptide - ENSP00000446867
Ensembl peptide - ENSP00000448868
NCBI entrez gene - 113675     See in Manteia.
RefSeq - XM_017018763
RefSeq - NM_001304993
RefSeq - NM_138432
RefSeq - XM_005253831
RefSeq - XM_011537846
RefSeq Peptide - NP_001291922
RefSeq Peptide - NP_612441
swissprot - F8VYZ3
swissprot - F8VZ97
swissprot - H0YIA2
swissprot - Q96GA7
swissprot - H0YID3
swissprot - A0A024RBL2
Ensembl - ENSG00000139410
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sdslENSDARG00000074698Danio rerio
 SDSLENSGALG00000008317Gallus gallus
 SdslENSMUSG00000029596Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SDS / P20132 / serine dehydrataseENSG0000013509460


Protein motifs (from Interpro)
Interpro ID Name
 IPR000634  Serine/threonine dehydratase, pyridoxal-phosphate-binding site
 IPR001926  Pyridoxal-phosphate dependent enzyme
 IPR036052  Tryptophan synthase beta subunit-like PLP-dependent enzyme


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006520 cellular amino acid metabolic process IEA
 biological_processGO:0008150 biological_process ND
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0003941 L-serine ammonia-lyase activity IEA
 molecular_functionGO:0004794 L-threonine ammonia-lyase activity IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0030170 pyridoxal phosphate binding IEA
 molecular_functionGO:0042802 identical protein binding IPI


Pathways (from Reactome)
Pathway description
Threonine catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000139410 SDSL / Q96GA7 / serine dehydratase like  / complex






 

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