ENSG00000135094


Homo sapiens

Features
Gene ID: ENSG00000135094
  
Biological name :SDS
  
Synonyms : P20132 / SDS / serine dehydratase
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q24.13
Gene start: 113392445
Gene end: 113426301
  
Corresponding Affymetrix probe sets: 1555539_at (Human Genome U133 Plus 2.0 Array)   205695_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000449061
Ensembl peptide - ENSP00000449833
Ensembl peptide - ENSP00000257549
NCBI entrez gene - 10993     See in Manteia.
OMIM - 182128
RefSeq - NM_006843
RefSeq Peptide - NP_006834
swissprot - P20132
swissprot - F8VW93
swissprot - F8VXS0
Ensembl - ENSG00000135094
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 SdsENSMUSG00000029597Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SDSL / Q96GA7 / serine dehydratase likeENSG0000013941060


Protein motifs (from Interpro)
Interpro ID Name
 IPR000634  Serine/threonine dehydratase, pyridoxal-phosphate-binding site
 IPR001926  Pyridoxal-phosphate dependent enzyme
 IPR036052  Tryptophan synthase beta subunit-like PLP-dependent enzyme


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006094 gluconeogenesis IEA
 biological_processGO:0006520 cellular amino acid metabolic process IEA
 biological_processGO:0006565 L-serine catabolic process IDA
 biological_processGO:0042866 pyruvate biosynthetic process IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0003941 L-serine ammonia-lyase activity IEA
 molecular_functionGO:0004794 L-threonine ammonia-lyase activity IEA
 molecular_functionGO:0016829 lyase activity IEA
 molecular_functionGO:0030170 pyridoxal phosphate binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IDA


Pathways (from Reactome)
Pathway description
Threonine catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000135094 SDS / P20132 / serine dehydratase  / complex






 

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