ENSG00000139436


Homo sapiens

Features
Gene ID: ENSG00000139436
  
Biological name :GIT2
  
Synonyms : GIT2 / GIT ArfGAP 2 / Q14161
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q24.11
Gene start: 109929792
Gene end: 109996389
  
Corresponding Affymetrix probe sets: 204982_at (Human Genome U133 Plus 2.0 Array)   209876_at (Human Genome U133 Plus 2.0 Array)   225558_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000473637
Ensembl peptide - ENSP00000448832
Ensembl peptide - ENSP00000450348
Ensembl peptide - ENSP00000323833
Ensembl peptide - ENSP00000346585
Ensembl peptide - ENSP00000347464
Ensembl peptide - ENSP00000354282
Ensembl peptide - ENSP00000391813
Ensembl peptide - ENSP00000447465
NCBI entrez gene - 9815     See in Manteia.
OMIM - 608564
RefSeq - XM_017020261
RefSeq - NM_057169
RefSeq - NM_057170
RefSeq - NM_139201
RefSeq - XM_005253997
RefSeq - XM_005254000
RefSeq - XM_006719707
RefSeq - XM_006719708
RefSeq - XM_006719709
RefSeq - XM_006719712
RefSeq - XM_006719713
RefSeq - XM_006719714
RefSeq - XM_017020258
RefSeq - XM_017020259
RefSeq - XM_017020260
RefSeq - NM_001135213
RefSeq - NM_001135214
RefSeq - NM_001330154
RefSeq - NM_014776
RefSeq Peptide - NP_476510
RefSeq Peptide - NP_001128685
RefSeq Peptide - NP_001128686
RefSeq Peptide - NP_001317082
RefSeq Peptide - NP_001317083
RefSeq Peptide - NP_055591
RefSeq Peptide - NP_476511
RefSeq Peptide - NP_631940
swissprot - R4GNG3
swissprot - F8WAK2
swissprot - Q14161
swissprot - Q6FI58
swissprot - F8W822
swissprot - F8VXI9
Ensembl - ENSG00000139436
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 git2aENSDARG00000061915Danio rerio
 git2bENSDARG00000042791Danio rerio
 GIT2ENSGALG00000040844Gallus gallus
 Git2ENSMUSG00000041890Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
GIT1 / Q9Y2X7 / GIT ArfGAP 1ENSG0000010826266


Protein motifs (from Interpro)
Interpro ID Name
 IPR001164  Arf GTPase activating protein
 IPR002110  Ankyrin repeat
 IPR013724  GIT, Spa2 homology (SHD) domain
 IPR020683  Ankyrin repeat-containing domain
 IPR022018  ARF GTPase-activating protein GIT1, C-terminal
 IPR032352  Arf GTPase-activating protein GIT1/2, coiled-coil domain
 IPR036770  Ankyrin repeat-containing domain superfamily
 IPR037278  ARFGAP/RecO-like zinc finger


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0008277 regulation of G-protein coupled receptor protein signaling pathway TAS
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005925 focal adhesion HDA
 molecular_functionGO:0005096 GTPase activator activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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