ENSG00000141030


Homo sapiens

Features
Gene ID: ENSG00000141030
  
Biological name :COPS3
  
Synonyms : COP9 signalosome subunit 3 / COPS3 / Q9UNS2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: p11.2
Gene start: 17246820
Gene end: 17281293
  
Corresponding Affymetrix probe sets: 202078_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000466153
Ensembl peptide - ENSP00000465156
Ensembl peptide - ENSP00000468536
Ensembl peptide - ENSP00000268717
Ensembl peptide - ENSP00000409028
Ensembl peptide - ENSP00000413298
Ensembl peptide - ENSP00000437606
Ensembl peptide - ENSP00000463098
Ensembl peptide - ENSP00000463195
Ensembl peptide - ENSP00000463340
Ensembl peptide - ENSP00000463477
Ensembl peptide - ENSP00000464369
Ensembl peptide - ENSP00000464572
NCBI entrez gene - 8533     See in Manteia.
OMIM - 604665
RefSeq - NM_001316354
RefSeq - XM_017025246
RefSeq - XM_005256842
RefSeq - XM_005256840
RefSeq - XM_005256837
RefSeq - NM_003653
RefSeq - NM_001316358
RefSeq - NM_001316357
RefSeq - NM_001316356
RefSeq - NM_001199125
RefSeq - NM_001316355
RefSeq Peptide - NP_003644
RefSeq Peptide - NP_001186054
RefSeq Peptide - NP_001303283
RefSeq Peptide - NP_001303284
RefSeq Peptide - NP_001303285
RefSeq Peptide - NP_001303286
RefSeq Peptide - NP_001303287
swissprot - J3QKR0
swissprot - J3KTQ1
swissprot - H7C3P9
swissprot - C9JLV5
swissprot - K7ES36
swissprot - K7ELN6
swissprot - K7EJF9
swissprot - J3QS85
swissprot - J3QL22
swissprot - Q9UNS2
Ensembl - ENSG00000141030
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cops3ENSDARG00000008623Danio rerio
 COPS3ENSGALG00000004834Gallus gallus
 Cops3ENSMUSG00000019373Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000717  Proteasome component (PCI) domain
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000338 protein deneddylation IDA
 biological_processGO:0000715 nucleotide-excision repair, DNA damage recognition TAS
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0006283 transcription-coupled nucleotide-excision repair TAS
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IBA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0009416 response to light stimulus TAS
 biological_processGO:0043687 post-translational protein modification TAS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0008180 COP9 signalosome IEA
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
DNA Damage Recognition in GG-NER
Formation of TC-NER Pre-Incision Complex
Cargo recognition for clathrin-mediated endocytosis
Neddylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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