ENSG00000141293


Homo sapiens

Features
Gene ID: ENSG00000141293
  
Biological name :SKAP1
  
Synonyms : Q86WV1 / SKAP1 / src kinase associated phosphoprotein 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q21.32
Gene start: 48133440
Gene end: 48430275
  
Corresponding Affymetrix probe sets: 205790_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000464509
Ensembl peptide - ENSP00000464198
Ensembl peptide - ENSP00000464311
Ensembl peptide - ENSP00000338171
Ensembl peptide - ENSP00000462360
Ensembl peptide - ENSP00000462437
Ensembl peptide - ENSP00000463284
NCBI entrez gene - 8631     See in Manteia.
OMIM - 604969
RefSeq - XM_017025260
RefSeq - NM_001075099
RefSeq - NM_003726
RefSeq - XM_005257755
RefSeq - XM_017025257
RefSeq - XM_017025258
RefSeq - XM_017025259
RefSeq Peptide - NP_001068567
RefSeq Peptide - NP_003717
swissprot - J3KSD4
swissprot - J3QKX8
swissprot - J3QRG3
swissprot - J3QS38
swissprot - Q86WV1
swissprot - J3KS83
Ensembl - ENSG00000141293
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 skap1ENSDARG00000001498Danio rerio
 SKAP1ENSGALG00000027305Gallus gallus
 Skap1ENSMUSG00000057058Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SKAP2 / O75563 / src kinase associated phosphoprotein 2ENSG0000000502035


Protein motifs (from Interpro)
Interpro ID Name
 IPR001452  SH3 domain
 IPR001849  Pleckstrin homology domain
 IPR011993  PH-like domain superfamily
 IPR035765  Src kinase-associated phosphoprotein 1, SH3 domain
 IPR036028  SH3-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002250 adaptive immune response IEA
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0009967 positive regulation of signal transduction IEA
 biological_processGO:0045785 positive regulation of cell adhesion IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IMP
 biological_processGO:0050852 T cell receptor signaling pathway IMP
 biological_processGO:0072659 protein localization to plasma membrane IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005911 cell-cell junction IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0042101 T cell receptor complex IEA
 molecular_functionGO:0005070 SH3/SH2 adaptor activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017124 SH3 domain binding TAS
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0019903 protein phosphatase binding IPI
 molecular_functionGO:0042169 SH2 domain binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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