ENSG00000141316


Homo sapiens

Features
Gene ID: ENSG00000141316
  
Biological name :SPACA3
  
Synonyms : Q8IXA5 / SPACA3 / sperm acrosome associated 3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q11.2
Gene start: 32970376
Gene end: 32997877
  
Corresponding Affymetrix probe sets: 243621_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000378134
Ensembl peptide - ENSP00000463386
Ensembl peptide - ENSP00000269053
NCBI entrez gene - 124912     See in Manteia.
OMIM - 612749
RefSeq - NM_001317225
RefSeq - NM_001317226
RefSeq - NM_173847
RefSeq Peptide - NP_776246
RefSeq Peptide - NP_001304154
RefSeq Peptide - NP_001304155
swissprot - Q8IXA5
swissprot - E9PF91
swissprot - A0A080YUZ7
Ensembl - ENSG00000141316
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q9D9X8ENSMUSG00000053184Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LYZL1 / Q6UWQ5 / lysozyme like 1ENSG0000012056334
LYZL2 / Q7Z4W2 / lysozyme like 2ENSG0000015103333
Q96QH8 / SPACA5B / sperm acrosome associated 5BENSG0000017147830
Q96QH8 / SPACA5 / sperm acrosome associated 5ENSG0000017148930
LYZ / P61626 / lysozymeENSG0000009038230
LYZL4 / Q96KX0 / lysozyme like 4ENSG0000015709330
LYZL6 / O75951 / lysozyme like 6ENSG0000027572229
LALBA / P00709 / lactalbumin alphaENSG0000016753121


Protein motifs (from Interpro)
Interpro ID Name
 IPR000974  Glycoside hydrolase, family 22, lysozyme
 IPR001916  Glycoside hydrolase, family 22
 IPR019799  Glycoside hydrolase, family 22, conserved site
 IPR023346  Lysozyme-like domain superfamily
 IPR030058  Lysozyme-like protein 3


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007342 fusion of sperm to egg plasma membrane involved in single fertilization IMP
 biological_processGO:0009253 peptidoglycan catabolic process TAS
 biological_processGO:0009566 fertilization IEA
 biological_processGO:0009615 response to virus TAS
 biological_processGO:0016998 cell wall macromolecule catabolic process TAS
 biological_processGO:0035036 sperm-egg recognition IEA
 biological_processGO:0042117 monocyte activation TAS
 biological_processGO:0043032 positive regulation of macrophage activation TAS
 biological_processGO:0050766 positive regulation of phagocytosis TAS
 biological_processGO:0050829 defense response to Gram-negative bacterium IBA
 biological_processGO:0050830 defense response to Gram-positive bacterium TAS
 cellular_componentGO:0001669 acrosomal vesicle IEA
 cellular_componentGO:0002080 acrosomal membrane IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030141 secretory granule IDA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0043159 acrosomal matrix IDA
 molecular_functionGO:0003796 lysozyme activity IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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