ENSG00000167531


Homo sapiens

Features
Gene ID: ENSG00000167531
  
Biological name :LALBA
  
Synonyms : lactalbumin alpha / LALBA / P00709
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q13.11
Gene start: 48567684
Gene end: 48570066
  
Corresponding Affymetrix probe sets: 207816_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000449780
Ensembl peptide - ENSP00000301046
NCBI entrez gene - 3906     See in Manteia.
OMIM - 149750
RefSeq - XM_006719395
RefSeq - NM_002289
RefSeq Peptide - NP_002280
swissprot - A0A080YV01
swissprot - P00709
swissprot - F8VWU1
Ensembl - ENSG00000167531
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LalbaENSMUSG00000022991Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
LYZ / P61626 / lysozymeENSG0000009038237
LYZL1 / Q6UWQ5 / lysozyme like 1ENSG0000012056335
LYZL2 / Q7Z4W2 / lysozyme like 2ENSG0000015103335
Q8IXA5 / SPACA3 / sperm acrosome associated 3ENSG0000014131632
Q96QH8 / SPACA5B / sperm acrosome associated 5BENSG0000017147831
Q96QH8 / SPACA5 / sperm acrosome associated 5ENSG0000017148931
LYZL4 / Q96KX0 / lysozyme like 4ENSG0000015709331
LYZL6 / O75951 / lysozyme like 6ENSG0000027572231


Protein motifs (from Interpro)
Interpro ID Name
 IPR000545  Lactalbumin
 IPR001916  Glycoside hydrolase, family 22
 IPR019799  Glycoside hydrolase, family 22, conserved site
 IPR023346  Lysozyme-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005989 lactose biosynthetic process IEA
 biological_processGO:0006915 apoptotic process TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007267 cell-cell signaling TAS
 biological_processGO:0016998 cell wall macromolecule catabolic process IBA
 biological_processGO:0042742 defense response to bacterium TAS
 biological_processGO:0050829 defense response to Gram-negative bacterium IBA
 biological_processGO:0050830 defense response to Gram-positive bacterium IBA
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space TAS
 cellular_componentGO:0005796 Golgi lumen TAS
 molecular_functionGO:0003796 lysozyme activity IBA
 molecular_functionGO:0004461 lactose synthase activity IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Lactose synthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000086062 P15291 / B4GALT1 / beta-1,4-galactosyltransferase 1  / reaction / complex






 

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