ENSG00000141401


Homo sapiens

Features
Gene ID: ENSG00000141401
  
Biological name :IMPA2
  
Synonyms : IMPA2 / inositol monophosphatase 2 / O14732
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 18
Strand: 1
Band: p11.21
Gene start: 11981025
Gene end: 12030883
  
Corresponding Affymetrix probe sets: 203126_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000486461
Ensembl peptide - ENSP00000465938
Ensembl peptide - ENSP00000466059
Ensembl peptide - ENSP00000269159
Ensembl peptide - ENSP00000372867
Ensembl peptide - ENSP00000464754
Ensembl peptide - ENSP00000464767
Ensembl peptide - ENSP00000465416
NCBI entrez gene - 3613     See in Manteia.
OMIM - 605922
RefSeq - XM_011525661
RefSeq - NM_014214
RefSeq - XM_011525659
RefSeq Peptide - NP_055029
swissprot - K7EIH6
swissprot - K7ELF8
swissprot - Q6PIP6
swissprot - K7EII9
swissprot - K7EL65
swissprot - O14732
Ensembl - ENSG00000141401
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 impa2ENSDARG00000059411Danio rerio
 IMPA2ENSGALG00000013814Gallus gallus
 Impa2ENSMUSG00000024525Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
IMPA1 / P29218 / inositol monophosphatase 1ENSG0000013373151


Protein motifs (from Interpro)
Interpro ID Name
 IPR000760  Inositol monophosphatase-like
 IPR020550  Inositol monophosphatase, conserved site
 IPR020552  Inositol monophosphatase, Lithium-sensitive
 IPR020583  Inositol monophosphatase, metal-binding site
 IPR033942  Inositol monophosphatase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006020 inositol metabolic process IBA
 biological_processGO:0006021 inositol biosynthetic process IEA
 biological_processGO:0006796 phosphate-containing compound metabolic process TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0043647 inositol phosphate metabolic process TAS
 biological_processGO:0046854 phosphatidylinositol phosphorylation IEA
 biological_processGO:0046855 inositol phosphate dephosphorylation IDA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008934 inositol monophosphate 1-phosphatase activity TAS
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0052832 inositol monophosphate 3-phosphatase activity TAS
 molecular_functionGO:0052833 inositol monophosphate 4-phosphatase activity TAS
 molecular_functionGO:0052834 inositol monophosphate phosphatase activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of IP2, IP, and Ins in the cytosol


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000141401 IMPA2 / O14732 / inositol monophosphatase 2  / complex






 

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