ENSG00000141934


Homo sapiens

Features
Gene ID: ENSG00000141934
  
Biological name :PLPP2
  
Synonyms : O43688 / phospholipid phosphatase 2 / PLPP2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: -1
Band: p13.3
Gene start: 281040
Gene end: 291504
  
Corresponding Affymetrix probe sets: 209529_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000466947
Ensembl peptide - ENSP00000466545
Ensembl peptide - ENSP00000488312
Ensembl peptide - ENSP00000269812
Ensembl peptide - ENSP00000329697
Ensembl peptide - ENSP00000388565
NCBI entrez gene - 8612     See in Manteia.
OMIM - 607126
RefSeq - XM_011528396
RefSeq - NM_003712
RefSeq - NM_177526
RefSeq - NM_177543
RefSeq Peptide - NP_803545
RefSeq Peptide - NP_003703
RefSeq Peptide - NP_808211
swissprot - O43688
swissprot - K7EMK9
swissprot - A0A0J9YXA3
swissprot - K7ENH4
Ensembl - ENSG00000141934
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 plpp2aENSDARG00000002231Danio rerio
 plpp2bENSDARG00000028896Danio rerio
 PLPP2ENSGALG00000026834Gallus gallus
 Plpp2ENSMUSG00000052151Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PLPP1 / O14494 / phospholipid phosphatase 1ENSG0000006711350
PLPP3 / O14495 / phospholipid phosphatase 3ENSG0000016240742
AC119674.2ENSG0000028468633
PLPPR3 / Q6T4P5 / phospholipid phosphatase related 3ENSG0000012995125
PLPPR4 / Q7Z2D5 / phospholipid phosphatase related 4ENSG0000011760023
PLPPR1 / Q8TBJ4 / phospholipid phosphatase related 1ENSG0000014812321
PLPPR2 / Q96GM1 / phospholipid phosphatase related 2ENSG0000010552020
PLPPR5 / Q32ZL2 / phospholipid phosphatase related 5ENSG0000011759819


Protein motifs (from Interpro)
Interpro ID Name
 IPR000326  Phosphatidic acid phosphatase type 2/haloperoxidase
 IPR028674  Lipid phosphate phosphohydrolase 2
 IPR036938  Phosphatidic acid phosphatase type 2/haloperoxidase superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006470 protein dephosphorylation IEA
 biological_processGO:0006644 phospholipid metabolic process IBA
 biological_processGO:0007165 signal transduction IBA
 biological_processGO:0016311 dephosphorylation IEA
 biological_processGO:0030148 sphingolipid biosynthetic process TAS
 biological_processGO:0046839 phospholipid dephosphorylation IBA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004721 phosphoprotein phosphatase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008195 phosphatidate phosphatase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0042392 sphingosine-1-phosphate phosphatase activity TAS
 molecular_functionGO:0042577 lipid phosphatase activity IBA


Pathways (from Reactome)
Pathway description
Sphingolipid de novo biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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