ENSG00000142149


Homo sapiens

Features
Gene ID: ENSG00000142149
  
Biological name :HUNK
  
Synonyms : hormonally up-regulated Neu-associated kinase / HUNK / P57058
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 21
Strand: 1
Band: q22.11
Gene start: 31873315
Gene end: 32044633
  
Corresponding Affymetrix probe sets: 1555935_s_at (Human Genome U133 Plus 2.0 Array)   219535_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000270112
Ensembl peptide - ENSP00000408219
Ensembl peptide - ENSP00000411860
NCBI entrez gene - 30811     See in Manteia.
OMIM - 606532
RefSeq - XM_011529537
RefSeq - NM_014586
RefSeq Peptide - NP_055401
swissprot - H7C2X2
swissprot - P57058
swissprot - H7C3H0
Ensembl - ENSG00000142149
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 hunkENSDARG00000091317Danio rerio
 HUNKENSGALG00000015879Gallus gallus
 HunkENSMUSG00000053414Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
MELK / Q14680 / maternal embryonic leucine zipper kinaseENSG0000016530422


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site
 IPR034671  Hormonally up-regulated neu tumour-associated kinase, catalytic domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007275 multicellular organism development TAS
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0035556 intracellular signal transduction IBA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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