ENSG00000142784


Homo sapiens

Features
Gene ID: ENSG00000142784
  
Biological name :WDTC1
  
Synonyms : Q8N5D0 / WD and tetratricopeptide repeats 1 / WDTC1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p36.11
Gene start: 27234516
Gene end: 27308633
  
Corresponding Affymetrix probe sets: 215497_s_at (Human Genome U133 Plus 2.0 Array)   216036_x_at (Human Genome U133 Plus 2.0 Array)   40829_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000317971
Ensembl peptide - ENSP00000355317
Ensembl peptide - ENSP00000434578
Ensembl peptide - ENSP00000435903
NCBI entrez gene - 23038     See in Manteia.
RefSeq - XM_011541058
RefSeq - NM_001276252
RefSeq - NM_015023
RefSeq - XM_011541057
RefSeq Peptide - NP_055838
RefSeq Peptide - NP_001263181
swissprot - Q8N5D0
swissprot - H0YEI6
Ensembl - ENSG00000142784
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 wdtc1ENSDARG00000059760Danio rerio
 WDTC1ENSGALG00000000943Gallus gallus
 Wdtc1ENSMUSG00000037622Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
DCAF6 / Q58WW2 / DDB1 and CUL4 associated factor 6ENSG0000014316426
AL139011.2ENSG0000025846521
DCAF8 / Q5TAQ9 / DDB1 and CUL4 associated factor 8ENSG0000013271621
P0C7V8 / DCAF8L2 / DDB1 and CUL4 associated factor 8 like 2ENSG0000018918620
A6NGE4 / DCAF8L1 / DDB1 and CUL4 associated factor 8 like 1ENSG0000022637219


Protein motifs (from Interpro)
Interpro ID Name
 IPR001680  WD40 repeat
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR017986  WD40-repeat-containing domain
 IPR019734  Tetratricopeptide repeat
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0006006 glucose metabolic process IEA
 biological_processGO:0008361 regulation of cell size IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0032869 cellular response to insulin stimulus IEA
 biological_processGO:0035264 multicellular organism growth IEA
 biological_processGO:0043086 negative regulation of catalytic activity IEA
 biological_processGO:0043687 post-translational protein modification TAS
 biological_processGO:0045717 negative regulation of fatty acid biosynthetic process IEA
 biological_processGO:0055082 cellular chemical homeostasis IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0004857 enzyme inhibitor activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042393 histone binding IEA
 molecular_functionGO:0042826 histone deacetylase binding IEA


Pathways (from Reactome)
Pathway description
Neddylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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