ENSG00000143321


Homo sapiens

Features
Gene ID: ENSG00000143321
  
Biological name :HDGF
  
Synonyms : HDGF / heparin binding growth factor / P51858
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q23.1
Gene start: 156742107
Gene end: 156766925
  
Corresponding Affymetrix probe sets: 200896_x_at (Human Genome U133 Plus 2.0 Array)   216484_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000349878
Ensembl peptide - ENSP00000357189
Ensembl peptide - ENSP00000357192
Ensembl peptide - ENSP00000443120
NCBI entrez gene - 3068     See in Manteia.
OMIM - 600339
RefSeq - NM_004494
RefSeq - XM_011509455
RefSeq - NM_001126050
RefSeq - NM_001126051
RefSeq - NM_001319186
RefSeq - NM_001319187
RefSeq - NM_001319188
RefSeq - XM_011509453
RefSeq - XM_011509454
RefSeq Peptide - NP_001306115
RefSeq Peptide - NP_001306117
RefSeq Peptide - NP_004485
RefSeq Peptide - NP_001306116
RefSeq Peptide - NP_001119522
RefSeq Peptide - NP_001119523
swissprot - P51858
Ensembl - ENSG00000143321
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000032847Gallus gallus
 HdgfENSMUSG00000004897Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HDGFL1 / Q5TGJ6 / HDGF like 1ENSG0000011227344
PSIP1 / O75475 / PC4 and SFRS1 interacting protein 1ENSG0000016498538
HDGFL2 / Q7Z4V5 / HDGF like 2ENSG0000016767435
HDGFL3 / Q9Y3E1 / HDGF like 3ENSG0000016650329


Protein motifs (from Interpro)
Interpro ID Name
 IPR000313  PWWP domain
 IPR035496  HDGF-related, PWWP domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007165 signal transduction NAS
 biological_processGO:0008283 cell proliferation TAS
 biological_processGO:0009987 cellular process IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0036498 IRE1-mediated unfolded protein response TAS
 cellular_componentGO:0005576 extracellular region IDA
 cellular_componentGO:0005615 extracellular space TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005737 cytoplasm TAS
 cellular_componentGO:0017053 transcriptional repressor complex IDA
 cellular_componentGO:0031012 extracellular matrix IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0001222 transcription corepressor binding IPI
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0008083 growth factor activity IEA
 molecular_functionGO:0008201 heparin binding TAS


Pathways (from Reactome)
Pathway description
XBP1(S) activates chaperone genes


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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