ENSMUSG00000004897


Mus musculus

Features
Gene ID: ENSMUSG00000004897
  
Biological name :Hdgf
  
Synonyms : Hdgf / Hepatoma-derived growth factor / P51859
  
Possible biological names infered from orthology : heparin binding growth factor / P51858
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: F1
Gene start: 87906321
Gene end: 87916132
  
Corresponding Affymetrix probe sets: 10493086 (MoGene1.0st)   1415888_at (Mouse Genome 430 2.0 Array)   1419964_s_at (Mouse Genome 430 2.0 Array)   1449681_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000123832
Ensembl peptide - ENSMUSP00000124803
Ensembl peptide - ENSMUSP00000005017
NCBI entrez gene - 15191     See in Manteia.
MGI - MGI:1194494
RefSeq - XM_006501027
RefSeq - XM_006501028
RefSeq - XM_006501029
RefSeq - NM_008231
RefSeq Peptide - NP_032257
swissprot - P51859
swissprot - E0CXA0
swissprot - E0CYW7
Ensembl - ENSMUSG00000004897
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000032847Gallus gallus
 HDGFENSG00000143321Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Psip1 / Q99JF8 / Mus musculus PC4 and SFRS1 interacting protein 1 (Psip1), transcript variant 3, mRNA. / O75475* / PC4 and SFRS1 interacting protein 1*ENSMUSG0000002848446
Hdgfl2 / Q3UMU9 / Mus musculus HDGF like 2 (Hdgfl2), transcript variant 4, mRNA. / Q7Z4V5* / HDGF like 2*ENSMUSG0000000283343
Hdgfl1 / Q5TGJ6* / HDGF like 1*ENSMUSG0000004583542
Hdgfl3 / Q9JMG7 / Hepatoma-derived growth factor-related protein 3 / Q9Y3E1* / HDGF like 3*ENSMUSG0000002510439


Protein motifs (from Interpro)
Interpro ID Name
 IPR000313  PWWP domain
 IPR035496  HDGF-related, PWWP domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0009987 cellular process IDA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0017053 transcriptional repressor complex IEA
 cellular_componentGO:0031012 extracellular matrix IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0001222 transcription corepressor binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008083 growth factor activity ISO
 molecular_functionGO:0008201 heparin binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002757 reduced vertical activity "lesser than average time spent jumping or rearing" [J:82829, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Polr2aTn(pb-CAG-GCaMP5g,-tdTomato)Tvrd/Polr2aTn(pb-CAG-GCaMP5g,-tdTomato)Tvrd
Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * C57BL/6NCr

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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