ENSG00000164985


Homo sapiens

Features
Gene ID: ENSG00000164985
  
Biological name :PSIP1
  
Synonyms : O75475 / PC4 and SFRS1 interacting protein 1 / PSIP1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: p22.3
Gene start: 15464066
Gene end: 15511019
  
Corresponding Affymetrix probe sets: 1554933_at (Human Genome U133 Plus 2.0 Array)   205961_s_at (Human Genome U133 Plus 2.0 Array)   209337_at (Human Genome U133 Plus 2.0 Array)   210758_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000477077
Ensembl peptide - ENSP00000370091
Ensembl peptide - ENSP00000370114
Ensembl peptide - ENSP00000380653
Ensembl peptide - ENSP00000370092
Ensembl peptide - ENSP00000370109
NCBI entrez gene - 11168     See in Manteia.
OMIM - 603620
RefSeq - NM_001317900
RefSeq - NM_001128217
RefSeq - NM_001317898
RefSeq - NM_021144
RefSeq - NM_033222
RefSeq Peptide - NP_001121689
RefSeq Peptide - NP_001304827
RefSeq Peptide - NP_001304829
RefSeq Peptide - NP_066967
RefSeq Peptide - NP_150091
swissprot - O75475
swissprot - V9GYT7
Ensembl - ENSG00000164985
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 psip1aENSDARG00000104710Danio rerio
 psip1bENSDARG00000077405Danio rerio
 PSIP1ENSGALG00000015105Gallus gallus
 Psip1ENSMUSG00000028484Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HDGFL2 / Q7Z4V5 / HDGF like 2ENSG0000016767438
HDGF / P51858 / heparin binding growth factorENSG0000014332118
HDGFL3 / Q9Y3E1 / HDGF like 3ENSG0000016650318
HDGFL1 / Q5TGJ6 / HDGF like 1ENSG0000011227316


Protein motifs (from Interpro)
Interpro ID Name
 IPR000313  PWWP domain
 IPR017859  Treacle-like, Treacher Collins Syndrome
 IPR021567  Lens epithelium-derived growth factor, integrase-binding domain
 IPR035496  HDGF-related, PWWP domain
 IPR036218  HIV integrase-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000395 mRNA 5"-splice site recognition IDA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006979 response to oxidative stress ISS
 biological_processGO:0009408 response to heat ISS
 biological_processGO:0016032 viral process IEA
 biological_processGO:0051169 nuclear transport TAS
 biological_processGO:0075713 establishment of integrated proviral latency TAS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0035327 transcriptionally active chromatin ISS
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003723 RNA binding HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0097100 supercoiled DNA binding ISS


Pathways (from Reactome)
Pathway description
Integration of provirus
2-LTR circle formation
Integration of viral DNA into host genomic DNA
Autointegration results in viral DNA circles
APOBEC3G mediated resistance to HIV-1 infection
Vpr-mediated nuclear import of PICs


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000175334 BANF1 / O75531 / barrier to autointegration factor 1  / complex / reaction
 ENSG00000137309 HMGA1 / P17096 / high mobility group AT-hook 1  / reaction / complex






 

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