ENSG00000143954


Homo sapiens

Features
Gene ID: ENSG00000143954
  
Biological name :REG3G
  
Synonyms : Q6UW15 / REG3G / regenerating family member 3 gamma
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: 1
Band: p12
Gene start: 79025686
Gene end: 79028505
  
Corresponding Affymetrix probe sets: 231661_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000272324
Ensembl peptide - ENSP00000377475
Ensembl peptide - ENSP00000387105
NCBI entrez gene - 130120     See in Manteia.
OMIM - 609933
RefSeq - XM_005264135
RefSeq - NM_001008387
RefSeq - NM_001270040
RefSeq - NM_198448
RefSeq Peptide - NP_001256969
RefSeq Peptide - NP_940850
RefSeq Peptide - NP_001008388
swissprot - Q6UW15
Ensembl - ENSG00000143954
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Reg3aENSMUSG00000079516Mus musculus
 Reg3bENSMUSG00000071356Mus musculus
 Reg3dENSMUSG00000068341Mus musculus
 Reg3gENSMUSG00000030017Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
REG3A / Q06141 / regenerating family member 3 alphaENSG0000017201685
REG1A / P05451 / regenerating family member 1 alphaENSG0000011538646
REG1B / P48304 / regenerating family member 1 betaENSG0000017202346
REG4 / Q9BYZ8 / regenerating family member 4ENSG0000013419329


Protein motifs (from Interpro)
Interpro ID Name
 IPR001304  C-type lectin-like
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR018378  C-type lectin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002755 MyD88-dependent toll-like receptor signaling pathway ISS
 biological_processGO:0006953 acute-phase response IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0010838 positive regulation of keratinocyte proliferation ISS
 biological_processGO:0019730 antimicrobial humoral response TAS
 biological_processGO:0044278 cell wall disruption in other organism IDA
 biological_processGO:0045617 negative regulation of keratinocyte differentiation ISS
 biological_processGO:0050830 defense response to Gram-positive bacterium ISS
 biological_processGO:0051715 cytolysis in other organism IDA
 biological_processGO:0061844 antimicrobial humoral immune response mediated by antimicrobial peptide IDA
 biological_processGO:0090303 positive regulation of wound healing ISS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0030246 carbohydrate binding IEA
 molecular_functionGO:0042834 peptidoglycan binding IDA
 molecular_functionGO:0070492 oligosaccharide binding IDA


Pathways (from Reactome)
Pathway description
Antimicrobial peptides


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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