ENSG00000172016


Homo sapiens

Features
Gene ID: ENSG00000172016
  
Biological name :REG3A
  
Synonyms : Q06141 / REG3A / regenerating family member 3 alpha
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 2
Strand: -1
Band: p12
Gene start: 79157003
Gene end: 79159753
  
Corresponding Affymetrix probe sets: 205815_at (Human Genome U133 Plus 2.0 Array)   234280_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000304311
Ensembl peptide - ENSP00000377456
Ensembl peptide - ENSP00000386630
NCBI entrez gene - 5068     See in Manteia.
OMIM - 167805
RefSeq - NM_138937
RefSeq - NM_002580
RefSeq - NM_138938
RefSeq Peptide - NP_002571
RefSeq Peptide - NP_620354
RefSeq Peptide - NP_620355
swissprot - Q06141
swissprot - Q53S56
Ensembl - ENSG00000172016
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Reg3aENSMUSG00000079516Mus musculus
 Reg3bENSMUSG00000071356Mus musculus
 Reg3dENSMUSG00000068341Mus musculus
 Reg3gENSMUSG00000030017Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
REG3G / Q6UW15 / regenerating family member 3 gammaENSG0000014395485
REG1A / P05451 / regenerating family member 1 alphaENSG0000011538648
REG1B / P48304 / regenerating family member 1 betaENSG0000017202346
REG4 / Q9BYZ8 / regenerating family member 4ENSG0000013419329


Protein motifs (from Interpro)
Interpro ID Name
 IPR001304  C-type lectin-like
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR018378  C-type lectin, conserved site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006953 acute-phase response IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules TAS
 biological_processGO:0007275 multicellular organism development TAS
 biological_processGO:0008283 cell proliferation TAS
 biological_processGO:0010838 positive regulation of keratinocyte proliferation ISS
 biological_processGO:0019730 antimicrobial humoral response TAS
 biological_processGO:0045617 negative regulation of keratinocyte differentiation ISS
 biological_processGO:0090303 positive regulation of wound healing ISS
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space TAS
 cellular_componentGO:0005737 cytoplasm TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030246 carbohydrate binding TAS
 molecular_functionGO:0042802 identical protein binding IPI


Pathways (from Reactome)
Pathway description
Antimicrobial peptides


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000172016 REG3A / Q06141 / regenerating family member 3 alpha  / complex / reaction






 

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