ENSG00000145041


Homo sapiens

Features
Gene ID: ENSG00000145041
  
Biological name :DCAF1
  
Synonyms : DCAF1 / DDB1 and CUL4 associated factor 1 / Q9Y4B6
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: -1
Band: p21.2
Gene start: 51395867
Gene end: 51500002
  
Corresponding Affymetrix probe sets: 204376_at (Human Genome U133 Plus 2.0 Array)   204377_s_at (Human Genome U133 Plus 2.0 Array)   226476_s_at (Human Genome U133 Plus 2.0 Array)   226477_at (Human Genome U133 Plus 2.0 Array)   226481_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000338857
Ensembl peptide - ENSP00000393183
Ensembl peptide - ENSP00000421724
NCBI entrez gene - 9730     See in Manteia.
OMIM - 617259
RefSeq - XM_017007551
RefSeq - NM_001171904
RefSeq - NM_014703
RefSeq - XM_011534277
RefSeq - XM_017007546
RefSeq - XM_017007547
RefSeq - XM_017007548
RefSeq - XM_017007549
RefSeq - XM_017007550
RefSeq - XM_005276753
RefSeq - XM_005276755
RefSeq - XM_011534273
RefSeq - XM_011534274
RefSeq - XM_011534275
RefSeq - XM_011534276
RefSeq Peptide - NP_001336097
RefSeq Peptide - NP_001336098
RefSeq Peptide - NP_001336099
RefSeq Peptide - NP_055518
RefSeq Peptide - NP_001165375
swissprot - Q9Y4B6
Ensembl - ENSG00000145041
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DCAF1ENSGALG00000033301Gallus gallus
 Dcaf1ENSMUSG00000040325Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006594  LIS1 homology motif
 IPR011989  Armadillo-like helical
 IPR015943  WD40/YVTN repeat-like-containing domain superfamily
 IPR016024  Armadillo-type fold
 IPR036322  WD40-repeat-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0016032 viral process IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0016567 protein ubiquitination IEA
 biological_processGO:0030183 B cell differentiation ISS
 biological_processGO:0033151 V(D)J recombination ISS
 biological_processGO:0035212 cell competition in a multicellular organism IMP
 biological_processGO:1990245 histone H2A-T120 phosphorylation IDA
 cellular_componentGO:0001650 fibrillar center IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0008180 COP9 signalosome IDA
 cellular_componentGO:0080008 Cul4-RING E3 ubiquitin ligase complex IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0030331 estrogen receptor binding IPI
 molecular_functionGO:1990244 histone kinase activity (H2A-T120 specific) IDA


Pathways (from Reactome)
Pathway description
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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