ENSG00000145391


Homo sapiens

Features
Gene ID: ENSG00000145391
  
Biological name :SETD7
  
Synonyms : Q8WTS6 / SETD7 / SET domain containing lysine methyltransferase 7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q31.1
Gene start: 139495941
Gene end: 139606699
  
Corresponding Affymetrix probe sets: 224928_at (Human Genome U133 Plus 2.0 Array)   244653_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000476302
Ensembl peptide - ENSP00000384336
Ensembl peptide - ENSP00000476712
Ensembl peptide - ENSP00000385913
Ensembl peptide - ENSP00000427300
Ensembl peptide - ENSP00000274031
NCBI entrez gene - 80854     See in Manteia.
OMIM - 606594
RefSeq - NM_001306200
RefSeq - XM_017008661
RefSeq - NM_030648
RefSeq - NM_001306199
RefSeq Peptide - NP_001293128
RefSeq Peptide - NP_001293129
RefSeq Peptide - NP_085151
swissprot - V9GYG1
swissprot - B5MCZ8
swissprot - Q8WTS6
swissprot - V9GY19
swissprot - B5MCS2
swissprot - D6RJA0
Ensembl - ENSG00000145391
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 setd7ENSDARG00000038858Danio rerio
 SETD7ENSGALG00000009800Gallus gallus
 Setd7ENSMUSG00000037111Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001214  SET domain
 IPR003409  MORN motif
 IPR017155  Histone-lysine N-methyltransferase, SET


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization NAS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IDA
 biological_processGO:0018022 peptidyl-lysine methylation IEA
 biological_processGO:0018026 peptidyl-lysine monomethylation IDA
 biological_processGO:0018027 peptidyl-lysine dimethylation IDA
 biological_processGO:0032259 methylation IEA
 biological_processGO:0034968 histone lysine methylation IEA
 biological_processGO:0045471 response to ethanol IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0051570 regulation of histone H3-K9 methylation IEA
 biological_processGO:0070828 heterochromatin organization IDA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005730 nucleolus IDA
 molecular_functionGO:0002039 p53 binding IPI
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0016279 protein-lysine N-methyltransferase activity IDA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0018024 histone-lysine N-methyltransferase activity TAS


Pathways (from Reactome)
Pathway description
PKMTs methylate histone lysines


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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