ENSG00000145425


Homo sapiens

Features
Gene ID: ENSG00000145425
  
Biological name :RPS3A
  
Synonyms : P61247 / ribosomal protein S3A / RPS3A
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: 1
Band: q31.3
Gene start: 151099573
Gene end: 151104652
  
Corresponding Affymetrix probe sets: 200099_s_at (Human Genome U133 Plus 2.0 Array)   201257_x_at (Human Genome U133 Plus 2.0 Array)   212391_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000421457
Ensembl peptide - ENSP00000421770
Ensembl peptide - ENSP00000426466
Ensembl peptide - ENSP00000426282
Ensembl peptide - ENSP00000425978
Ensembl peptide - ENSP00000425508
Ensembl peptide - ENSP00000425024
Ensembl peptide - ENSP00000424547
Ensembl peptide - ENSP00000423953
Ensembl peptide - ENSP00000422994
Ensembl peptide - ENSP00000421776
Ensembl peptide - ENSP00000346050
Ensembl peptide - ENSP00000421277
NCBI entrez gene - 6189     See in Manteia.
OMIM - 180478
RefSeq - NM_001267699
RefSeq - NM_001006
RefSeq Peptide - NP_000997
RefSeq Peptide - NP_001254628
swissprot - D6RED7
swissprot - D6RB09
swissprot - D6RAT0
swissprot - D6RAS7
swissprot - D6R9B6
swissprot - H0Y8L7
swissprot - H0Y9Y4
swissprot - E9PFI5
swissprot - P61247
swissprot - D6RI02
swissprot - D6RGE0
swissprot - D6RG13
Ensembl - ENSG00000145425
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rps3aENSDARG00000035692Danio rerio
 RPS3AENSGALG00000010077Gallus gallus
 P97351ENSMUSG00000028081Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001593  Ribosomal protein S3Ae
 IPR018281  Ribosomal protein S3Ae, conserved site
 IPR027500  40S ribosomal protein S1/3, eukaryotes


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS
 biological_processGO:0002181 cytoplasmic translation IBA
 biological_processGO:0006364 rRNA processing TAS
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation TAS
 biological_processGO:0006614 SRP-dependent cotranslational protein targeting to membrane TAS
 biological_processGO:0019083 viral transcription TAS
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005730 nucleolus IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IDA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005840 ribosome IEA
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0022627 cytosolic small ribosomal subunit IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003723 RNA binding NAS
 molecular_functionGO:0003735 structural constituent of ribosome IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0048027 mRNA 5"-UTR binding IDA


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
Major pathway of rRNA processing in the nucleolus and cytosol
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Regulation of expression of SLITs and ROBOs
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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