ENSG00000145708


Homo sapiens

Features
Gene ID: ENSG00000145708
  
Biological name :CRHBP
  
Synonyms : corticotropin releasing hormone binding protein / CRHBP / P24387
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: 1
Band: q13.3
Gene start: 76952713
Gene end: 76981158
  
Corresponding Affymetrix probe sets: 205984_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000274368
Ensembl peptide - ENSP00000426097
NCBI entrez gene - 1393     See in Manteia.
OMIM - 122559
RefSeq - NM_001882
RefSeq Peptide - NP_001873
swissprot - D6RHH7
swissprot - P24387
Ensembl - ENSG00000145708
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 crhbpENSDARG00000024831Danio rerio
 CRHBPENSGALG00000014994Gallus gallus
 CrhbpENSMUSG00000021680Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR008435  Corticotropin-releasing factor-binding protein
 IPR035914  Spermadhesin, CUB domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001963 synaptic transmission, dopaminergic IEA
 biological_processGO:0002125 maternal aggressive behavior IEA
 biological_processGO:0006954 inflammatory response IDA
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0007565 female pregnancy IEP
 biological_processGO:0007611 learning or memory TAS
 biological_processGO:0009755 hormone-mediated signaling pathway IDA
 biological_processGO:0035690 cellular response to drug IEA
 biological_processGO:0035865 cellular response to potassium ion IDA
 biological_processGO:0042445 hormone metabolic process IEA
 biological_processGO:0045055 regulated exocytosis IDA
 biological_processGO:0048149 behavioral response to ethanol IMP
 biological_processGO:0051459 regulation of corticotropin secretion IDA
 biological_processGO:0051460 negative regulation of corticotropin secretion IDA
 biological_processGO:0071277 cellular response to calcium ion IEA
 biological_processGO:0071314 cellular response to cocaine ISS
 biological_processGO:0071320 cellular response to cAMP IEA
 biological_processGO:0071356 cellular response to tumor necrosis factor IDA
 biological_processGO:0071391 cellular response to estrogen stimulus IDA
 biological_processGO:0071392 cellular response to estradiol stimulus IEA
 biological_processGO:0080135 regulation of cellular response to stress IMP
 biological_processGO:0097211 cellular response to gonadotropin-releasing hormone IEA
 biological_processGO:1900011 negative regulation of corticotropin-releasing hormone receptor activity IDA
 biological_processGO:2000310 regulation of NMDA receptor activity IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005767 secondary lysosome ISS
 cellular_componentGO:0005771 multivesicular body ISS
 cellular_componentGO:0005874 microtubule ISS
 cellular_componentGO:0030141 secretory granule IDA
 cellular_componentGO:0030425 dendrite ISS
 cellular_componentGO:0031045 dense core granule ISS
 cellular_componentGO:0043196 varicosity ISS
 cellular_componentGO:0043204 perikaryon ISS
 cellular_componentGO:0043679 axon terminus ISS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042277 peptide binding ISS
 molecular_functionGO:0051424 corticotropin-releasing hormone binding IEA


Pathways (from Reactome)
Pathway description
Class B/2 (Secretin family receptors)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000147571 CRH / P06850 / corticotropin releasing hormone  / reaction / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr