ENSG00000146453


Homo sapiens

Features
Gene ID: ENSG00000146453
  
Biological name :PNLDC1
  
Synonyms : PARN like, ribonuclease domain containing 1 / PNLDC1 / Q8NA58
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: q25.3
Gene start: 159800249
Gene end: 159820704
  
Corresponding Affymetrix probe sets: 1564414_a_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000275275
Ensembl peptide - ENSP00000376007
Ensembl peptide - ENSP00000476448
Ensembl peptide - ENSP00000476544
Ensembl peptide - ENSP00000476769
NCBI entrez gene - 154197     See in Manteia.
RefSeq - XM_017010316
RefSeq - NM_001271862
RefSeq - NM_173516
RefSeq - XM_017010312
RefSeq - XM_017010313
RefSeq - XM_017010314
RefSeq - XM_017010315
RefSeq - XM_011535491
RefSeq - XM_011535493
RefSeq Peptide - NP_775787
RefSeq Peptide - NP_001258791
swissprot - Q8NA58
swissprot - V9GYA0
Ensembl - ENSG00000146453
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 PNLDC1ENSGALG00000011624Gallus gallus
 B2RXZ1ENSMUSG00000073460Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PARN / O95453 / poly(A)-specific ribonucleaseENSG0000014069425


Protein motifs (from Interpro)
Interpro ID Name
 IPR006941  Ribonuclease CAF1
 IPR012337  Ribonuclease H-like superfamily
 IPR036397  Ribonuclease H superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IEA
 biological_processGO:0000289 nuclear-transcribed mRNA poly(A) tail shortening IDA
 biological_processGO:0090305 nucleic acid phosphodiester bond hydrolysis IEA
 biological_processGO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003723 RNA binding IEA
 molecular_functionGO:0004518 nuclease activity IEA
 molecular_functionGO:0004527 exonuclease activity IEA
 molecular_functionGO:0004535 poly(A)-specific ribonuclease activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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