ENSG00000147604


Homo sapiens

Features
Gene ID: ENSG00000147604
  
Biological name :RPL7
  
Synonyms : P18124 / ribosomal protein L7 / RPL7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: -1
Band: q21.11
Gene start: 73290267
Gene end: 73295789
  
Corresponding Affymetrix probe sets: 200717_x_at (Human Genome U133 Plus 2.0 Array)   212042_x_at (Human Genome U133 Plus 2.0 Array)   239493_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000401300
Ensembl peptide - ENSP00000379729
Ensembl peptide - ENSP00000415808
Ensembl peptide - ENSP00000379730
Ensembl peptide - ENSP00000379731
Ensembl peptide - ENSP00000339795
NCBI entrez gene - 6129     See in Manteia.
OMIM - 604166
RefSeq - NM_000971
RefSeq - XM_006716463
RefSeq Peptide - NP_000962
swissprot - A8MUD9
swissprot - C9JZ88
swissprot - P18124
swissprot - C9JIJ5
Ensembl - ENSG00000147604
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rpl7ENSDARG00000007320Danio rerio
 RPL7ENSGALG00000035252Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q6DKI1 / RPL7L1 / ribosomal protein L7 like 1ENSG0000014622343


Protein motifs (from Interpro)
Interpro ID Name
 IPR005998  Ribosomal protein L7, eukaryotic
 IPR012988  Ribosomal protein L30, N-terminal
 IPR016082  Ribosomal protein L30, ferredoxin-like fold domain
 IPR018038  Ribosomal protein L30, conserved site
 IPR035808  Ribosomal protein L7, eukaryotic/archaeal
 IPR036919  Ribosomal protein L30, ferredoxin-like fold domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay TAS
 biological_processGO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
 biological_processGO:0002181 cytoplasmic translation IBA
 biological_processGO:0006364 rRNA processing TAS
 biological_processGO:0006412 translation TAS
 biological_processGO:0006413 translational initiation TAS
 biological_processGO:0006614 SRP-dependent cotranslational protein targeting to membrane TAS
 biological_processGO:0019083 viral transcription TAS
 biological_processGO:0042273 ribosomal large subunit biogenesis IMP
 cellular_componentGO:0005634 nucleus HDA
 cellular_componentGO:0005730 nucleolus HDA
 cellular_componentGO:0005737 cytoplasm HDA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005840 ribosome IEA
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0022625 cytosolic large ribosomal subunit TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0003723 RNA binding TAS
 molecular_functionGO:0003729 mRNA binding IDA
 molecular_functionGO:0003735 structural constituent of ribosome TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IPI


Pathways (from Reactome)
Pathway description
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
Major pathway of rRNA processing in the nucleolus and cytosol
Formation of a pool of free 40S subunits
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Regulation of expression of SLITs and ROBOs
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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