ENSG00000147853


Homo sapiens

Features
Gene ID: ENSG00000147853
  
Biological name :AK3
  
Synonyms : adenylate kinase 3 / AK3 / Q9UIJ7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: p24.1
Gene start: 4709559
Gene end: 4742043
  
Corresponding Affymetrix probe sets: 224151_s_at (Human Genome U133 Plus 2.0 Array)   224655_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000352948
Ensembl peptide - ENSP00000371230
Ensembl peptide - ENSP00000413933
Ensembl peptide - ENSP00000482308
NCBI entrez gene - 50808     See in Manteia.
OMIM - 609290
RefSeq - NM_001199855
RefSeq - NM_001199852
RefSeq - NM_001199853
RefSeq - NM_001199856
RefSeq - NM_016282
RefSeq Peptide - NP_001186781
RefSeq Peptide - NP_001186782
RefSeq Peptide - NP_001186784
RefSeq Peptide - NP_001186785
RefSeq Peptide - NP_057366
swissprot - Q9UIJ7
Ensembl - ENSG00000147853
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ak3ENSDARG00000058226Danio rerio
 AK3ENSGALG00000014447Gallus gallus
 Ak3ENSMUSG00000024782Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AK4 / P27144 / adenylate kinase 4ENSG0000016243356


Protein motifs (from Interpro)
Interpro ID Name
 IPR000850  Adenylate kinase/UMP-CMP kinase
 IPR006259  Adenylate kinase subfamily
 IPR007862  Adenylate kinase, active site lid domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR028586  Adenylate kinase 3/4, mitochondrial
 IPR033690  Adenylate kinase, conserved site
 IPR036193  Adenylate kinase, active site lid domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006139 nucleobase-containing compound metabolic process IEA
 biological_processGO:0007596 blood coagulation TAS
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0046033 AMP metabolic process IDA
 biological_processGO:0046039 GTP metabolic process IDA
 biological_processGO:0046041 ITP metabolic process IDA
 biological_processGO:0046051 UTP metabolic process IDA
 cellular_componentGO:0005739 mitochondrion ISS
 cellular_componentGO:0005759 mitochondrial matrix ISS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004017 adenylate kinase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016776 phosphotransferase activity, phosphate group as acceptor IEA
 molecular_functionGO:0019205 nucleobase-containing compound kinase activity IEA
 molecular_functionGO:0046899 nucleoside triphosphate adenylate kinase activity EXP


Pathways (from Reactome)
Pathway description
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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