ENSG00000162433


Homo sapiens

Features
Gene ID: ENSG00000162433
  
Biological name :AK4
  
Synonyms : adenylate kinase 4 / AK4 / P27144
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: 1
Band: p31.3
Gene start: 65147549
Gene end: 65232145
  
Corresponding Affymetrix probe sets: 204347_at (Human Genome U133 Plus 2.0 Array)   204348_s_at (Human Genome U133 Plus 2.0 Array)   225342_at (Human Genome U133 Plus 2.0 Array)   230630_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000448458
Ensembl peptide - ENSP00000322175
Ensembl peptide - ENSP00000378743
Ensembl peptide - ENSP00000445912
NCBI entrez gene - 205     See in Manteia.
OMIM - 103030
RefSeq - XM_017000613
RefSeq - NM_001005353
RefSeq - NM_001330616
RefSeq - NM_013410
RefSeq - NM_203464
RefSeq - XM_017000612
RefSeq Peptide - NP_001317545
RefSeq Peptide - NP_037542
RefSeq Peptide - NP_982289
RefSeq Peptide - NP_001005353
swissprot - P27144
swissprot - D3DQ64
Ensembl - ENSG00000162433
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ak4ENSDARG00000006546Danio rerio
 AK4ENSGALG00000011035Gallus gallus
 Ak4ENSMUSG00000028527Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AK3 / Q9UIJ7 / adenylate kinase 3ENSG0000014785357


Protein motifs (from Interpro)
Interpro ID Name
 IPR000850  Adenylate kinase/UMP-CMP kinase
 IPR006259  Adenylate kinase subfamily
 IPR007862  Adenylate kinase, active site lid domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR028585  Adenylate kinase 4, mitochondrial
 IPR028586  Adenylate kinase 3/4, mitochondrial
 IPR033690  Adenylate kinase, conserved site
 IPR036193  Adenylate kinase, active site lid domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001889 liver development IEA
 biological_processGO:0006139 nucleobase-containing compound metabolic process IEA
 biological_processGO:0006165 nucleoside diphosphate phosphorylation IDA
 biological_processGO:0007420 brain development IEA
 biological_processGO:0009142 nucleoside triphosphate biosynthetic process IDA
 biological_processGO:0015949 nucleobase-containing small molecule interconversion TAS
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0046033 AMP metabolic process IDA
 biological_processGO:0046034 ATP metabolic process IDA
 biological_processGO:0046039 GTP metabolic process IDA
 biological_processGO:0046939 nucleotide phosphorylation IEA
 biological_processGO:0046940 nucleoside monophosphate phosphorylation IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005759 mitochondrial matrix ISS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004017 adenylate kinase activity IDA
 molecular_functionGO:0004550 nucleoside diphosphate kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016776 phosphotransferase activity, phosphate group as acceptor IEA
 molecular_functionGO:0019205 nucleobase-containing compound kinase activity IEA
 molecular_functionGO:0046899 nucleoside triphosphate adenylate kinase activity IDA
 molecular_functionGO:0050145 nucleoside monophosphate kinase activity TAS


Pathways (from Reactome)
Pathway description
Interconversion of nucleotide di- and triphosphates


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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