ENSMUSG00000028527


Mus musculus

Features
Gene ID: ENSMUSG00000028527
  
Biological name :Ak4
  
Synonyms : Adenylate kinase 4, mitochondrial / Ak4 / Q9WUR9
  
Possible biological names infered from orthology : adenylate kinase 4 / P27144
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: C6
Gene start: 101419277
Gene end: 101466995
  
Corresponding Affymetrix probe sets: 10472923 (MoGene1.0st)   10506269 (MoGene1.0st)   1421829_at (Mouse Genome 430 2.0 Array)   1421830_at (Mouse Genome 430 2.0 Array)   1421831_at (Mouse Genome 430 2.0 Array)   1438395_at (Mouse Genome 430 2.0 Array)   1450387_s_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000115456
Ensembl peptide - ENSMUSP00000115454
Ensembl peptide - ENSMUSP00000121112
Ensembl peptide - ENSMUSP00000099841
Ensembl peptide - ENSMUSP00000102558
Ensembl peptide - ENSMUSP00000102559
NCBI entrez gene - 11639     See in Manteia.
MGI - MGI:87979
RefSeq - XM_017319923
RefSeq - NM_001177602
RefSeq - NM_001177604
RefSeq - NM_001177605
RefSeq - NM_009647
RefSeq - XM_006502685
RefSeq Peptide - NP_001171075
RefSeq Peptide - NP_033777
RefSeq Peptide - NP_001171076
RefSeq Peptide - NP_001171073
swissprot - A2ARF5
swissprot - Q9WUR9
swissprot - F6TEU8
swissprot - A2ARF6
swissprot - Q3U489
Ensembl - ENSMUSG00000028527
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ak4ENSDARG00000006546Danio rerio
 AK4ENSGALG00000011035Gallus gallus
 AK4ENSG00000162433Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ak3 / Q9WTP7 / GTP:AMP phosphotransferase AK3, mitochondrial / Q9UIJ7* / adenylate kinase 3*ENSMUSG0000002478256


Protein motifs (from Interpro)
Interpro ID Name
 IPR000850  Adenylate kinase/UMP-CMP kinase
 IPR006259  Adenylate kinase subfamily
 IPR007862  Adenylate kinase, active site lid domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR028585  Adenylate kinase 4, mitochondrial
 IPR028586  Adenylate kinase 3/4, mitochondrial
 IPR033690  Adenylate kinase, conserved site
 IPR036193  Adenylate kinase, active site lid domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001889 liver development IEA
 biological_processGO:0006139 nucleobase-containing compound metabolic process IEA
 biological_processGO:0006165 nucleoside diphosphate phosphorylation ISO
 biological_processGO:0006172 ADP biosynthetic process IEA
 biological_processGO:0007420 brain development IEA
 biological_processGO:0009142 nucleoside triphosphate biosynthetic process ISS
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0046033 AMP metabolic process IEA
 biological_processGO:0046034 ATP metabolic process IEA
 biological_processGO:0046039 GTP metabolic process IEA
 biological_processGO:0046939 nucleotide phosphorylation IEA
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005759 mitochondrial matrix IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004017 adenylate kinase activity IEA
 molecular_functionGO:0004550 nucleoside diphosphate kinase activity ISO
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016776 phosphotransferase activity, phosphate group as acceptor IEA
 molecular_functionGO:0019205 nucleobase-containing compound kinase activity IEA
 molecular_functionGO:0046899 nucleoside triphosphate adenylate kinase activity IEA


Pathways (from Reactome)
Pathway description
Interconversion of nucleotide di- and triphosphates


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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