ENSMUSG00000024782


Mus musculus

Features
Gene ID: ENSMUSG00000024782
  
Biological name :Ak3
  
Synonyms : Ak3 / GTP:AMP phosphotransferase AK3, mitochondrial / Q9WTP7
  
Possible biological names infered from orthology : adenylate kinase 3 / Q9UIJ7
  
Species: Mus musculus
  
Chr. number: 19
Strand: -1
Band: C1
Gene start: 29020833
Gene end: 29047961
  
Corresponding Affymetrix probe sets: 10466925 (MoGene1.0st)   1423717_at (Mouse Genome 430 2.0 Array)   1423718_at (Mouse Genome 430 2.0 Array)   1432436_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000025696
Ensembl peptide - ENSMUSP00000121867
NCBI entrez gene - 56248     See in Manteia.
MGI - MGI:1860835
RefSeq - NM_021299
RefSeq - XM_006527222
RefSeq Peptide - NP_067274
swissprot - F6RP11
swissprot - Q9WTP7
Ensembl - ENSMUSG00000024782
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ak3ENSDARG00000058226Danio rerio
 AK3ENSGALG00000014447Gallus gallus
 AK3ENSG00000147853Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ak4 / Q9WUR9 / Adenylate kinase 4, mitochondrial / P27144* / adenylate kinase 4*ENSMUSG0000002852755


Protein motifs (from Interpro)
Interpro ID Name
 IPR000850  Adenylate kinase/UMP-CMP kinase
 IPR006259  Adenylate kinase subfamily
 IPR007862  Adenylate kinase, active site lid domain
 IPR027417  P-loop containing nucleoside triphosphate hydrolase
 IPR028586  Adenylate kinase 3/4, mitochondrial
 IPR033690  Adenylate kinase, conserved site
 IPR036193  Adenylate kinase, active site lid domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006139 nucleobase-containing compound metabolic process IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0046033 AMP metabolic process IEA
 biological_processGO:0046039 GTP metabolic process IEA
 biological_processGO:0046041 ITP metabolic process IEA
 biological_processGO:0046051 UTP metabolic process IEA
 biological_processGO:0046939 nucleotide phosphorylation IEA
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005759 mitochondrial matrix IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004017 adenylate kinase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0005525 GTP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016776 phosphotransferase activity, phosphate group as acceptor IEA
 molecular_functionGO:0019205 nucleobase-containing compound kinase activity IEA
 molecular_functionGO:0046899 nucleoside triphosphate adenylate kinase activity ISO


Pathways (from Reactome)
Pathway description
Factors involved in megakaryocyte development and platelet production


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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