ENSG00000148248


Homo sapiens

Features
Gene ID: ENSG00000148248
  
Biological name :SURF4
  
Synonyms : O15260 / SURF4 / surfeit 4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 9
Strand: -1
Band: q34.2
Gene start: 133361449
Gene end: 133376166
  
Corresponding Affymetrix probe sets: 222977_at (Human Genome U133 Plus 2.0 Array)   222978_at (Human Genome U133 Plus 2.0 Array)   222979_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000481666
Ensembl peptide - ENSP00000446061
Ensembl peptide - ENSP00000483216
Ensembl peptide - ENSP00000361057
Ensembl peptide - ENSP00000361059
Ensembl peptide - ENSP00000419853
NCBI entrez gene - 6836     See in Manteia.
OMIM - 185660
RefSeq - XM_017015062
RefSeq - NM_001280788
RefSeq - NM_001280789
RefSeq - NM_001280790
RefSeq - NM_001280791
RefSeq - NM_001280792
RefSeq - NM_001280793
RefSeq - NM_033161
RefSeq - XM_011518943
RefSeq - XM_011518944
RefSeq - XM_011518945
RefSeq Peptide - NP_001267720
RefSeq Peptide - NP_001267721
RefSeq Peptide - NP_001267722
RefSeq Peptide - NP_149351
RefSeq Peptide - NP_001267717
RefSeq Peptide - NP_001267718
RefSeq Peptide - NP_001267719
swissprot - O15260
swissprot - Q5T8U5
swissprot - B7Z1G8
Ensembl - ENSG00000148248
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 surf4lENSDARG00000035131Danio rerio
 SURF4ENSGALG00000028265Gallus gallus
 Surf4ENSMUSG00000014867Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002995  Surfeit locus 4


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006890 retrograde vesicle-mediated transport, Golgi to ER TAS
 biological_processGO:0007030 Golgi organization IMP
 biological_processGO:0010638 positive regulation of organelle organization IMP
 biological_processGO:0043312 neutrophil degranulation TAS
 cellular_componentGO:0000139 Golgi membrane TAS
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0005793 endoplasmic reticulum-Golgi intermediate compartment IDA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030133 transport vesicle TAS
 cellular_componentGO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane IEA
 cellular_componentGO:0035577 azurophil granule membrane TAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
COPI-dependent Golgi-to-ER retrograde traffic


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000086598 TMED2 / Q15363 / transmembrane p24 trafficking protein 2  / complex
 ENSG00000170348 P49755 / TMED10 / transmembrane p24 trafficking protein 10  / complex
 ENSG00000184840 TMED9 / Q9BVK6 / transmembrane p24 trafficking protein 9  / complex






 

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contact: otassy@igbmc.fr