ENSG00000148832


Homo sapiens

Features
Gene ID: ENSG00000148832
  
Biological name :PAOX
  
Synonyms : PAOX / polyamine oxidase / Q6QHF9
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: 1
Band: q26.3
Gene start: 133379234
Gene end: 133391694
  
Corresponding Affymetrix probe sets: 221941_at (Human Genome U133 Plus 2.0 Array)   238333_s_at (Human Genome U133 Plus 2.0 Array)   50400_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000434550
Ensembl peptide - ENSP00000435514
Ensembl peptide - ENSP00000278060
Ensembl peptide - ENSP00000348654
Ensembl peptide - ENSP00000349847
Ensembl peptide - ENSP00000432517
Ensembl peptide - ENSP00000432737
NCBI entrez gene - 196743     See in Manteia.
OMIM - 615853
RefSeq - NM_152911
RefSeq - NM_207127
RefSeq - NM_207128
RefSeq Peptide - NP_690875
RefSeq Peptide - NP_997010
RefSeq Peptide - NP_997011
swissprot - Q6QHF9
Ensembl - ENSG00000148832
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LO018020.1ENSDARG00000109596Danio rerio
 si:dkey-275b16.2ENSDARG00000003380Danio rerio
 PAOXENSGALG00000003557Gallus gallus
 PaoxENSMUSG00000025464Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SMOX / Q9NWM0 / spermine oxidaseENSG0000008882642
KDM1A / O60341 / lysine demethylase 1AENSG0000000448727
KDM1B / Q8NB78 / lysine demethylase 1BENSG0000016509722


Protein motifs (from Interpro)
Interpro ID Name
 IPR002937  Amine oxidase
 IPR036188  FAD/NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006596 polyamine biosynthetic process TAS
 biological_processGO:0006598 polyamine catabolic process IEA
 biological_processGO:0008215 spermine metabolic process IEA
 biological_processGO:0009446 putrescine biosynthetic process IDA
 biological_processGO:0009447 putrescine catabolic process IDA
 biological_processGO:0046203 spermidine catabolic process IDA
 biological_processGO:0046208 spermine catabolic process IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:1901307 positive regulation of spermidine biosynthetic process IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005777 peroxisome IEA
 cellular_componentGO:0005782 peroxisomal matrix TAS
 molecular_functionGO:0005102 signaling receptor binding IPI
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0046592 polyamine oxidase activity IDA
 molecular_functionGO:0052899 N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity IEA
 molecular_functionGO:0052901 spermine:oxygen oxidoreductase (spermidine-forming) activity IEA
 molecular_functionGO:0052902 spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity IEA
 molecular_functionGO:0052903 N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity IEA
 molecular_functionGO:0052904 N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity TAS


Pathways (from Reactome)
Pathway description
PAOs oxidise polyamines to amines
Interconversion of polyamines
Peroxisomal protein import


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr