ENSMUSG00000025464


Mus musculus

Features
Gene ID: ENSMUSG00000025464
  
Biological name :Paox
  
Synonyms : Mus musculus polyamine oxidase (exo-N4-amino) (Paox), transcript variant 2, mRNA. / Paox / Q8C0L6
  
Possible biological names infered from orthology : polyamine oxidase / Q6QHF9
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: F4
Gene start: 140115799
Gene end: 140137224
  
Corresponding Affymetrix probe sets: 10345203 (MoGene1.0st)   10558596 (MoGene1.0st)   1428859_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000147852
Ensembl peptide - ENSMUSP00000026537
Ensembl peptide - ENSMUSP00000095580
Ensembl peptide - ENSMUSP00000147545
NCBI entrez gene - 212503     See in Manteia.
MGI - MGI:1916983
RefSeq - XM_017322103
RefSeq - XM_006536166
RefSeq - XM_006536167
RefSeq - XM_006536168
RefSeq - XM_006536169
RefSeq - XM_011249839
RefSeq - XM_017322102
RefSeq - NM_001346725
RefSeq - NM_153783
RefSeq Peptide - NP_001333654
RefSeq Peptide - NP_722478
swissprot - A0A1B0GS98
swissprot - Q8C0L6
swissprot - A0A1B0GRJ2
swissprot - Q3TXR6
Ensembl - ENSMUSG00000025464
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 LO018020.1ENSDARG00000109596Danio rerio
 si:dkey-275b16.2ENSDARG00000003380Danio rerio
 PAOXENSGALG00000003557Gallus gallus
 PAOXENSG00000148832Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Smox / Q99K82 / spermine oxidase / Q9NWM0*ENSMUSG0000002733341
Kdm1b / Q8CIG3 / Lysine-specific histone demethylase 1B / Q8NB78* / lysine demethylase 1B*ENSMUSG0000003808025
Kdm1a / Q6ZQ88 / Mus musculus lysine (K)-specific demethylase 1A (Kdm1a), transcript variant 3, mRNA. / O60341* / lysine demethylase 1A*ENSMUSG0000003694025


Protein motifs (from Interpro)
Interpro ID Name
 IPR002937  Amine oxidase
 IPR036188  FAD/NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006598 polyamine catabolic process IEA
 biological_processGO:0008215 spermine metabolic process IEA
 biological_processGO:0009446 putrescine biosynthetic process IEA
 biological_processGO:0009447 putrescine catabolic process IEA
 biological_processGO:0046203 spermidine catabolic process IEA
 biological_processGO:0046208 spermine catabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:1901307 positive regulation of spermidine biosynthetic process IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005777 peroxisome IEA
 cellular_componentGO:0005782 peroxisomal matrix IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0046592 polyamine oxidase activity IEA
 molecular_functionGO:0052899 N(1),N(12)-diacetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity IEA
 molecular_functionGO:0052901 spermine:oxygen oxidoreductase (spermidine-forming) activity IEA
 molecular_functionGO:0052902 spermidine:oxygen oxidoreductase (3-aminopropanal-forming) activity IEA
 molecular_functionGO:0052903 N1-acetylspermine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity IEA
 molecular_functionGO:0052904 N1-acetylspermidine:oxygen oxidoreductase (3-acetamidopropanal-forming) activity IEA


Pathways (from Reactome)
Pathway description
PAOs oxidise polyamines to amines
Interconversion of polyamines
Peroxisomal protein import


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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