ENSMUSG00000038080


Mus musculus

Features
Gene ID: ENSMUSG00000038080
  
Biological name :Kdm1b
  
Synonyms : Kdm1b / Lysine-specific histone demethylase 1B / Q8CIG3
  
Possible biological names infered from orthology : lysine demethylase 1B / Q8NB78
  
Species: Mus musculus
  
Chr. number: 13
Strand: 1
Band: A5
Gene start: 47043499
Gene end: 47085279
  
Corresponding Affymetrix probe sets: 10404941 (MoGene1.0st)   1433649_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000038373
Ensembl peptide - ENSMUSP00000114999
Ensembl peptide - ENSMUSP00000117793
NCBI entrez gene - 218214     See in Manteia.
MGI - MGI:2145261
RefSeq - XM_006516920
RefSeq - XM_006516914
RefSeq - XM_006516915
RefSeq - XM_006516916
RefSeq - XM_006516917
RefSeq - NM_172262
RefSeq - XM_006516913
RefSeq Peptide - NP_758466
swissprot - F6V3V2
swissprot - D3Z353
swissprot - Q8CIG3
Ensembl - ENSMUSG00000038080
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KDM1BENSGALG00000012685Gallus gallus
 KDM1BENSG00000165097Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Kdm1a / Q6ZQ88 / Mus musculus lysine (K)-specific demethylase 1A (Kdm1a), transcript variant 3, mRNA. / O60341* / lysine demethylase 1A*ENSMUSG0000003694027
Paox / Q8C0L6 / Mus musculus polyamine oxidase (exo-N4-amino) (Paox), transcript variant 2, mRNA. / Q6QHF9* / polyamine oxidase*ENSMUSG0000002546415
Smox / Q99K82 / spermine oxidase / Q9NWM0*ENSMUSG0000002733315


Protein motifs (from Interpro)
Interpro ID Name
 IPR002937  Amine oxidase
 IPR007526  SWIRM domain
 IPR009057  Homeobox-like domain superfamily
 IPR011124  Zinc finger, CW-type
 IPR036188  FAD/NAD(P)-binding domain superfamily
 IPR036388  Winged helix-like DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006349 regulation of gene expression by genetic imprinting IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0034720 histone H3-K4 demethylation IEA
 biological_processGO:0043046 DNA methylation involved in gamete generation IMP
 biological_processGO:0044030 regulation of DNA methylation IMP
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0000786 nucleosome IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0034648 histone demethylase activity (H3-dimethyl-K4 specific) IEA
 molecular_functionGO:0034649 histone demethylase activity (H3-monomethyl-K4 specific) IDA
 molecular_functionGO:0042393 histone binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0050660 flavin adenine dinucleotide binding IDA
 molecular_functionGO:0071949 FAD binding IEA


Pathways (from Reactome)
Pathway description
HDMs demethylate histones
UCH proteinases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001926 female infertility "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
Show

Allelic Composition: Slc34a1tm1Hten/Slc34a1tm1Hten
Genetic Background: B6.129S2-Slc34a1tm1Hten/J

 MP:0003718 maternal effect "expression of a phenotypic trait in an female animal s offspring that is dependent on the maternal genotype" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Slc34a1tm1Hten/Slc34a1tm1Hten
Genetic Background: B6.129S2-Slc34a1tm1Hten/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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