ENSMUSG00000027333


Mus musculus

Features
Gene ID: ENSMUSG00000027333
  
Biological name :Smox
  
Synonyms : Q99K82 / Smox / spermine oxidase
  
Possible biological names infered from orthology : Q9NWM0
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: F1
Gene start: 131491496
Gene end: 131525922
  
Corresponding Affymetrix probe sets: 10476301 (MoGene1.0st)   1424268_at (Mouse Genome 430 2.0 Array)   1446509_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000139099
Ensembl peptide - ENSMUSP00000120237
Ensembl peptide - ENSMUSP00000139111
Ensembl peptide - ENSMUSP00000139278
Ensembl peptide - ENSMUSP00000028806
Ensembl peptide - ENSMUSP00000105808
Ensembl peptide - ENSMUSP00000105809
Ensembl peptide - ENSMUSP00000105810
Ensembl peptide - ENSMUSP00000105811
Ensembl peptide - ENSMUSP00000105812
Ensembl peptide - ENSMUSP00000105815
Ensembl peptide - ENSMUSP00000105817
Ensembl peptide - ENSMUSP00000105818
Ensembl peptide - ENSMUSP00000114956
NCBI entrez gene - 228608     See in Manteia.
MGI - MGI:2445356
RefSeq - XM_017317769
RefSeq - NM_001177833
RefSeq - NM_001177834
RefSeq - NM_001177835
RefSeq - NM_001177836
RefSeq - NM_001177837
RefSeq - NM_001177838
RefSeq - NM_001177839
RefSeq - NM_001177840
RefSeq - NM_145533
RefSeq - XM_006499287
RefSeq - XM_006499288
RefSeq - XM_006499289
RefSeq - XM_006499290
RefSeq - XM_006499291
RefSeq - XM_006499292
RefSeq - XM_006499293
RefSeq - XM_011239475
RefSeq Peptide - NP_001171311
RefSeq Peptide - NP_663508
RefSeq Peptide - NP_001171304
RefSeq Peptide - NP_001171305
RefSeq Peptide - NP_001171306
RefSeq Peptide - NP_001171307
RefSeq Peptide - NP_001171308
RefSeq Peptide - NP_001171309
RefSeq Peptide - NP_001171310
swissprot - V9GXD6
swissprot - A2ANQ4
swissprot - Q3TLR8
swissprot - Q3UPW5
swissprot - Q99K82
swissprot - A2AP08
swissprot - V9GXE5
swissprot - A2ANQ3
Ensembl - ENSMUSG00000027333
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 smoxENSDARG00000036967Danio rerio
 SMOXENSGALG00000015977Gallus gallus
 SMOXENSG00000088826Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Paox / Q8C0L6 / Mus musculus polyamine oxidase (exo-N4-amino) (Paox), transcript variant 2, mRNA. / Q6QHF9* / polyamine oxidase*ENSMUSG0000002546435
Kdm1a / Q6ZQ88 / Mus musculus lysine (K)-specific demethylase 1A (Kdm1a), transcript variant 3, mRNA. / O60341* / lysine demethylase 1A*ENSMUSG0000003694025
Kdm1b / Q8CIG3 / Lysine-specific histone demethylase 1B / Q8NB78* / lysine demethylase 1B*ENSMUSG0000003808022


Protein motifs (from Interpro)
Interpro ID Name
 IPR002937  Amine oxidase
 IPR036188  FAD/NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006598 polyamine catabolic process ISO
 biological_processGO:0046208 spermine catabolic process IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031965 nuclear membrane ISO
 cellular_componentGO:0043231 intracellular membrane-bounded organelle ISO
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0046592 polyamine oxidase activity ISO
 molecular_functionGO:0052894 norspermine:oxygen oxidoreductase activity IEA
 molecular_functionGO:0052895 N1-acetylspermine:oxygen oxidoreductase (N1-acetylspermidine-forming) activity IEA
 molecular_functionGO:0052901 spermine:oxygen oxidoreductase (spermidine-forming) activity IEA


Pathways (from Reactome)
Pathway description
PAOs oxidise polyamines to amines
Interconversion of polyamines


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ace2tm1Lex/Y
Genetic Background: B6;129S5-Ace2tm1Lex/Mmucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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