ENSG00000165097


Homo sapiens

Features
Gene ID: ENSG00000165097
  
Biological name :KDM1B
  
Synonyms : KDM1B / lysine demethylase 1B / Q8NB78
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: p22.3
Gene start: 18155329
Gene end: 18223853
  
Corresponding Affymetrix probe sets: 1553150_at (Human Genome U133 Plus 2.0 Array)   227021_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000297792
Ensembl peptide - ENSP00000405669
Ensembl peptide - ENSP00000442670
NCBI entrez gene - 221656     See in Manteia.
OMIM - 613081
RefSeq - XM_017010445
RefSeq - NM_153042
RefSeq - XM_017010440
RefSeq - XM_017010441
RefSeq - XM_017010442
RefSeq - XM_017010443
RefSeq - XM_005248925
RefSeq - XM_005248926
RefSeq - XM_005248928
RefSeq - XM_011514385
RefSeq - XM_011514386
RefSeq Peptide - NP_694587
swissprot - Q08EI0
swissprot - Q8NB78
swissprot - H0Y6H0
Ensembl - ENSG00000165097
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 KDM1BENSGALG00000012685Gallus gallus
 Kdm1bENSMUSG00000038080Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KDM1A / O60341 / lysine demethylase 1AENSG0000000448731
SMOX / Q9NWM0 / spermine oxidaseENSG0000008882620
PAOX / Q6QHF9 / polyamine oxidaseENSG0000014883219


Protein motifs (from Interpro)
Interpro ID Name
 IPR002937  Amine oxidase
 IPR007526  SWIRM domain
 IPR009057  Homeobox-like domain superfamily
 IPR011124  Zinc finger, CW-type
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR036188  FAD/NAD(P)-binding domain superfamily
 IPR036388  Winged helix-like DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006349 regulation of gene expression by genetic imprinting IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0016579 protein deubiquitination TAS
 biological_processGO:0034720 histone H3-K4 demethylation IEA
 biological_processGO:0043046 DNA methylation involved in gamete generation IEA
 biological_processGO:0044030 regulation of DNA methylation IEA
 biological_processGO:0055114 oxidation-reduction process IEA
 cellular_componentGO:0000786 nucleosome IDA
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005654 nucleoplasm TAS
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008270 zinc ion binding IDA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0032452 histone demethylase activity TAS
 molecular_functionGO:0034648 histone demethylase activity (H3-dimethyl-K4 specific) IEA
 molecular_functionGO:0034649 histone demethylase activity (H3-monomethyl-K4 specific) ISS
 molecular_functionGO:0042393 histone binding IDA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0050660 flavin adenine dinucleotide binding IEA
 molecular_functionGO:0071949 FAD binding IDA


Pathways (from Reactome)
Pathway description
HDMs demethylate histones
UCH proteinases


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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