ENSG00000149735


Homo sapiens

Features
Gene ID: ENSG00000149735
  
Biological name :GPHA2
  
Synonyms : glycoprotein hormone alpha 2 / GPHA2 / Q96T91
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: -1
Band: q13.1
Gene start: 64934471
Gene end: 64935888
  
Corresponding Affymetrix probe sets: 237230_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000279168
Ensembl peptide - ENSP00000432918
Ensembl peptide - ENSP00000431352
NCBI entrez gene - 170589     See in Manteia.
OMIM - 609651
RefSeq - XM_011544774
RefSeq - XM_011544776
RefSeq - NM_130769
RefSeq - XM_011544775
RefSeq Peptide - NP_570125
swissprot - Q96T91
swissprot - E9PLQ0
swissprot - A0A024R579
Ensembl - ENSG00000149735
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gpha2ENSDARG00000075403Danio rerio
 Gpha2ENSMUSG00000024784Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000476  Glycoprotein hormone alpha chain
 IPR006207  Cystine knot, C-terminal
 IPR029034  Cystine-knot cytokine


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007166 cell surface receptor signaling pathway IMP
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0030819 obsolete positive regulation of cAMP biosynthetic process IMP
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion IMP
 cellular_componentGO:0005576 extracellular region IDA
 molecular_functionGO:0005179 hormone activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0031531 thyrotropin-releasing hormone receptor binding IMP
 molecular_functionGO:0046982 protein heterodimerization activity IDA


Pathways (from Reactome)
Pathway description
Hormone ligand-binding receptors
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000179600 GPHB5 / Q86YW7 / glycoprotein hormone beta 5  / complex
 ENSG00000165409 TSHR / P16473 / thyroid stimulating hormone receptor  / reaction / complex






 

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contact: otassy@igbmc.fr