ENSMUSG00000024784


Mus musculus

Features
Gene ID: ENSMUSG00000024784
  
Biological name :Gpha2
  
Synonyms : glycoprotein hormone alpha 2 / Gpha2 / Q925Q5
  
Possible biological names infered from orthology : Q96T91
  
Species: Mus musculus
  
Chr. number: 19
Strand: 1
Band: A
Gene start: 6226380
Gene end: 6227768
  
Corresponding Affymetrix probe sets: 10460782 (MoGene1.0st)   1421497_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000109154
Ensembl peptide - ENSMUSP00000025698
NCBI entrez gene - 170458     See in Manteia.
MGI - MGI:2156541
RefSeq - NM_130453
RefSeq Peptide - NP_569720
swissprot - A2RSW3
swissprot - Q925Q5
Ensembl - ENSMUSG00000024784
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gpha2ENSDARG00000075403Danio rerio
 GPHA2ENSG00000149735Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000476  Glycoprotein hormone alpha chain
 IPR004133  DAN
 IPR006207  Cystine knot, C-terminal
 IPR029034  Cystine-knot cytokine


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007166 cell surface receptor signaling pathway ISO
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0030819 obsolete positive regulation of cAMP biosynthetic process ISO
 biological_processGO:1903955 positive regulation of protein targeting to mitochondrion ISO
 cellular_componentGO:0005576 extracellular region ISO
 molecular_functionGO:0005179 hormone activity IEA
 molecular_functionGO:0031531 thyrotropin-releasing hormone receptor binding ISO
 molecular_functionGO:0046982 protein heterodimerization activity IEA


Pathways (from Reactome)
Pathway description
Hormone ligand-binding receptors
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000020963 Tshr / P47750 / thyroid stimulating hormone receptor / P16473*  / reaction / complex
 ENSMUSG00000048982 Gphb5 / Q812B2 / glycoprotein hormone beta 5 / Q86YW7*  / complex






 

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contact: otassy@igbmc.fr