ENSG00000179600


Homo sapiens

Features
Gene ID: ENSG00000179600
  
Biological name :GPHB5
  
Synonyms : glycoprotein hormone beta 5 / GPHB5 / Q86YW7
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: -1
Band: q23.2
Gene start: 63312835
Gene end: 63318879
  
Corresponding Affymetrix probe sets: 1553945_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000478993
Ensembl peptide - ENSP00000479431
NCBI entrez gene - 122876     See in Manteia.
OMIM - 609652
RefSeq - NM_145171
RefSeq Peptide - NP_660154
swissprot - A0A0F7RPU1
swissprot - Q86YW7
Ensembl - ENSG00000179600
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gphb5ENSDARG00000027472Danio rerio
 GPHB5ENSGALG00000028839Gallus gallus
 Gphb5ENSMUSG00000048982Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001545  Gonadotropin, beta subunit
 IPR006208  Glycoprotein hormone subunit beta
 IPR029034  Cystine-knot cytokine


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002155 regulation of thyroid hormone mediated signaling pathway IBA
 biological_processGO:0007166 cell surface receptor signaling pathway IMP
 biological_processGO:0007186 G-protein coupled receptor signaling pathway TAS
 biological_processGO:0007267 cell-cell signaling IBA
 biological_processGO:0009755 hormone-mediated signaling pathway IBA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0030819 obsolete positive regulation of cAMP biosynthetic process IMP
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IBA
 cellular_componentGO:0005737 cytoplasm IBA
 molecular_functionGO:0005179 hormone activity IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0031531 thyrotropin-releasing hormone receptor binding IMP
 molecular_functionGO:0046982 protein heterodimerization activity IDA


Pathways (from Reactome)
Pathway description
Hormone ligand-binding receptors
G alpha (s) signalling events


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000149735 GPHA2 / Q96T91 / glycoprotein hormone alpha 2  / complex
 ENSG00000165409 TSHR / P16473 / thyroid stimulating hormone receptor  / reaction / complex






 

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