ENSG00000150281


Homo sapiens

Features
Gene ID: ENSG00000150281
  
Biological name :CTF1
  
Synonyms : cardiotrophin 1 / CTF1 / Q16619
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: 1
Band: p11.2
Gene start: 30896607
Gene end: 30903560
  
Corresponding Affymetrix probe sets: 206813_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000279804
Ensembl peptide - ENSP00000378465
NCBI entrez gene - 1489     See in Manteia.
OMIM - 600435
RefSeq - XM_011545760
RefSeq - NM_001142544
RefSeq - NM_001330
RefSeq - XM_011545759
RefSeq Peptide - NP_001136016
RefSeq Peptide - NP_001321
swissprot - Q16619
Ensembl - ENSG00000150281
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Ctf1ENSMUSG00000042340Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR009079  Four-helical cytokine-like, core
 IPR010681  Plethodontid receptivity factor PRF/cardiotrophin-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007166 cell surface receptor signaling pathway IBA
 biological_processGO:0007267 cell-cell signaling TAS
 biological_processGO:0007399 nervous system development TAS
 biological_processGO:0007517 muscle organ development TAS
 biological_processGO:0008283 cell proliferation TAS
 biological_processGO:0008284 positive regulation of cell proliferation TAS
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway TAS
 biological_processGO:0042531 positive regulation of tyrosine phosphorylation of STAT protein IDA
 biological_processGO:0048666 neuron development IEA
 biological_processGO:0048861 leukemia inhibitory factor signaling pathway IEA
 cellular_componentGO:0005576 extracellular region IBA
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0005125 cytokine activity IBA
 molecular_functionGO:0005146 leukemia inhibitory factor receptor binding TAS
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
IL-6-type cytokine receptor ligand interactions


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000162434 JAK1 / P23458 / Janus kinase 1  / reaction / complex
 ENSG00000096968 JAK2 / O60674 / Janus kinase 2  / reaction / complex
 ENSG00000113594 LIFR / P42702 / LIF receptor alpha  / reaction / complex
 ENSG00000134352 IL6ST / P40189 / interleukin 6 signal transducer  / reaction / complex






 

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