ENSG00000151012


Homo sapiens

Features
Gene ID: ENSG00000151012
  
Biological name :SLC7A11
  
Synonyms : Q9UPY5 / SLC7A11 / solute carrier family 7 member 11
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q28.3
Gene start: 138164097
Gene end: 138242349
  
Corresponding Affymetrix probe sets: 207528_s_at (Human Genome U133 Plus 2.0 Array)   209921_at (Human Genome U133 Plus 2.0 Array)   217678_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000280612
Ensembl peptide - ENSP00000424046
NCBI entrez gene - 23657     See in Manteia.
OMIM - 607933
RefSeq - XM_011531802
RefSeq - NM_014331
RefSeq Peptide - NP_055146
swissprot - Q9UPY5
swissprot - H0Y9F9
Ensembl - ENSG00000151012
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc7a11ENSDARG00000071384Danio rerio
 SLC7A11ENSGALG00000009758Gallus gallus
 Q9WTR6ENSMUSG00000027737Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q01650 / SLC7A5 / solute carrier family 7 member 5ENSG0000010325745
Q92536 / SLC7A6 / solute carrier family 7 member 6ENSG0000010306444
Q9UM01 / SLC7A7 / solute carrier family 7 member 7ENSG0000015546543
Q9UHI5 / SLC7A8 / solute carrier family 7 member 8ENSG0000009206842
Q9NS82 / SLC7A10 / solute carrier family 7 member 10ENSG0000013087641
P82251 / SLC7A9 / solute carrier family 7 member 9ENSG0000002148841
Q8TCU3 / SLC7A13 / solute carrier family 7 member 13ENSG0000016489328


Protein motifs (from Interpro)
Interpro ID Name
 IPR002293  Amino acid/polyamine transporter I
 IPR004760  L-type amino acid transporter


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006865 amino acid transport TAS
 biological_processGO:0006979 response to oxidative stress IEA
 biological_processGO:0007420 brain development IEA
 biological_processGO:0009636 response to toxic substance IDA
 biological_processGO:0015813 L-glutamate transmembrane transport IEA
 biological_processGO:0035094 response to nicotine IEA
 biological_processGO:0050900 leukocyte migration TAS
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0070306 lens fiber cell differentiation IEA
 biological_processGO:0070527 platelet aggregation IEA
 cellular_componentGO:0005791 rough endoplasmic reticulum IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane TAS
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015327 cystine:glutamate antiporter activity TAS
 molecular_functionGO:0022857 transmembrane transporter activity IEA


Pathways (from Reactome)
Pathway description
Basigin interactions
Amino acid transport across the plasma membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000168003 P08195 / SLC3A2 / solute carrier family 3 member 2  / complex






 

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