ENSG00000103257


Homo sapiens

Features
Gene ID: ENSG00000103257
  
Biological name :SLC7A5
  
Synonyms : Q01650 / SLC7A5 / solute carrier family 7 member 5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 16
Strand: -1
Band: q24.2
Gene start: 87830023
Gene end: 87869488
  
Corresponding Affymetrix probe sets: 201195_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000454323
Ensembl peptide - ENSP00000261622
NCBI entrez gene - 8140     See in Manteia.
OMIM - 600182
RefSeq - XM_017023737
RefSeq - NM_003486
RefSeq - XM_006721286
RefSeq - XM_017023735
RefSeq - XM_017023736
RefSeq Peptide - NP_003477
swissprot - Q01650
swissprot - A0A0C4DGL4
Ensembl - ENSG00000103257
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc7a5ENSDARG00000099265Danio rerio
 SLC7A5ENSGALG00000005845Gallus gallus
 Q9Z127ENSMUSG00000040010Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9UHI5 / SLC7A8 / solute carrier family 7 member 8ENSG0000009206851
Q9UM01 / SLC7A7 / solute carrier family 7 member 7ENSG0000015546547
Q92536 / SLC7A6 / solute carrier family 7 member 6ENSG0000010306446
Q9NS82 / SLC7A10 / solute carrier family 7 member 10ENSG0000013087645
Q9UPY5 / SLC7A11 / solute carrier family 7 member 11ENSG0000015101245
P82251 / SLC7A9 / solute carrier family 7 member 9ENSG0000002148841
Q8TCU3 / SLC7A13 / solute carrier family 7 member 13ENSG0000016489327


Protein motifs (from Interpro)
Interpro ID Name
 IPR002293  Amino acid/polyamine transporter I
 IPR004760  L-type amino acid transporter


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006520 cellular amino acid metabolic process TAS
 biological_processGO:0006865 amino acid transport IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0015804 neutral amino acid transport ISS
 biological_processGO:0015807 L-amino acid transport IEA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0050900 leukocyte migration TAS
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:1902475 L-alpha-amino acid transmembrane transport TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005886 plasma membrane NAS
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane HDA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016324 apical plasma membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015171 amino acid transmembrane transporter activity ISS
 molecular_functionGO:0015175 neutral amino acid transmembrane transporter activity TAS
 molecular_functionGO:0015179 L-amino acid transmembrane transporter activity IEA
 molecular_functionGO:0015297 antiporter activity IBA
 molecular_functionGO:0022857 transmembrane transporter activity IEA
 molecular_functionGO:0042605 peptide antigen binding ISS


Pathways (from Reactome)
Pathway description
Basigin interactions
Amino acid transport across the plasma membrane
Tryptophan catabolism


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000168003 P08195 / SLC3A2 / solute carrier family 3 member 2  / complex






 

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