ENSG00000092068


Homo sapiens

Features
Gene ID: ENSG00000092068
  
Biological name :SLC7A8
  
Synonyms : Q9UHI5 / SLC7A8 / solute carrier family 7 member 8
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: -1
Band: q11.2
Gene start: 23125295
Gene end: 23183674
  
Corresponding Affymetrix probe sets: 202752_x_at (Human Genome U133 Plus 2.0 Array)   216092_s_at (Human Genome U133 Plus 2.0 Array)   216603_at (Human Genome U133 Plus 2.0 Array)   216604_s_at (Human Genome U133 Plus 2.0 Array)   217248_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000416398
Ensembl peptide - ENSP00000480181
Ensembl peptide - ENSP00000436665
Ensembl peptide - ENSP00000435865
Ensembl peptide - ENSP00000435114
Ensembl peptide - ENSP00000434352
Ensembl peptide - ENSP00000434345
Ensembl peptide - ENSP00000320378
Ensembl peptide - ENSP00000343949
Ensembl peptide - ENSP00000391577
NCBI entrez gene - 23428     See in Manteia.
OMIM - 604235
RefSeq - NM_182728
RefSeq - NM_012244
RefSeq - NM_001267036
RefSeq - NM_001267037
RefSeq Peptide - NP_877392
RefSeq Peptide - NP_001253965
RefSeq Peptide - NP_001253966
RefSeq Peptide - NP_036376
swissprot - Q9UHI5
swissprot - E9PQT4
swissprot - E9PLV9
swissprot - E9PIC3
swissprot - A0A087WWF3
swissprot - H0Y2X7
swissprot - E9PS92
Ensembl - ENSG00000092068
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 slc7a8aENSDARG00000075831Danio rerio
 slc7a8bENSDARG00000054343Danio rerio
 Q9QXW9ENSMUSG00000022180Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q9NS82 / SLC7A10 / solute carrier family 7 member 10ENSG0000013087662
Q01650 / SLC7A5 / solute carrier family 7 member 5ENSG0000010325748
Q92536 / SLC7A6 / solute carrier family 7 member 6ENSG0000010306445
Q9UM01 / SLC7A7 / solute carrier family 7 member 7ENSG0000015546545
Q9UPY5 / SLC7A11 / solute carrier family 7 member 11ENSG0000015101240
P82251 / SLC7A9 / solute carrier family 7 member 9ENSG0000002148838
Q8TCU3 / SLC7A13 / solute carrier family 7 member 13ENSG0000016489327


Protein motifs (from Interpro)
Interpro ID Name
 IPR002293  Amino acid/polyamine transporter I
 IPR004760  L-type amino acid transporter


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003333 amino acid transmembrane transport IEA
 biological_processGO:0006520 cellular amino acid metabolic process TAS
 biological_processGO:0006865 amino acid transport TAS
 biological_processGO:0009636 response to toxic substance NAS
 biological_processGO:0015695 organic cation transport IEA
 biological_processGO:0015804 neutral amino acid transport ISS
 biological_processGO:0015807 L-amino acid transport IEA
 biological_processGO:0050900 leukocyte migration TAS
 biological_processGO:0055065 metal ion homeostasis NAS
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:1901998 toxin transport IEA
 biological_processGO:1902475 L-alpha-amino acid transmembrane transport IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015101 organic cation transmembrane transporter activity IDA
 molecular_functionGO:0015171 amino acid transmembrane transporter activity ISS
 molecular_functionGO:0015175 neutral amino acid transmembrane transporter activity TAS
 molecular_functionGO:0015179 L-amino acid transmembrane transporter activity IBA
 molecular_functionGO:0015297 antiporter activity IBA
 molecular_functionGO:0019534 toxin transmembrane transporter activity IDA
 molecular_functionGO:0022857 transmembrane transporter activity IEA
 molecular_functionGO:0042605 peptide antigen binding ISS


Pathways (from Reactome)
Pathway description
Basigin interactions
Amino acid transport across the plasma membrane


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000168003 P08195 / SLC3A2 / solute carrier family 3 member 2  / complex






 

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