ENSG00000151239


Homo sapiens

Features
Gene ID: ENSG00000151239
  
Biological name :TWF1
  
Synonyms : Q12792 / TWF1 / twinfilin actin binding protein 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 12
Strand: -1
Band: q12
Gene start: 43793723
Gene end: 43806375
  
Corresponding Affymetrix probe sets: 201745_at (Human Genome U133 Plus 2.0 Array)   214007_s_at (Human Genome U133 Plus 2.0 Array)   214008_at (Human Genome U133 Plus 2.0 Array)   243033_at (Human Genome U133 Plus 2.0 Array)   244199_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000446696
Ensembl peptide - ENSP00000448682
Ensembl peptide - ENSP00000448750
Ensembl peptide - ENSP00000449428
Ensembl peptide - ENSP00000378886
Ensembl peptide - ENSP00000446665
Ensembl peptide - ENSP00000448221
Ensembl peptide - ENSP00000448230
NCBI entrez gene - 5756     See in Manteia.
OMIM - 610932
RefSeq - NM_001242397
RefSeq - NM_002822
RefSeq Peptide - NP_001229326
RefSeq Peptide - NP_002813
swissprot - Q12792
swissprot - F8VRG3
swissprot - F8VS81
swissprot - F8W1D0
swissprot - F8W1Q9
swissprot - F8W645
Ensembl - ENSG00000151239
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TWF1 (1 of many)ENSDARG00000115712Danio rerio
 twf1bENSDARG00000011661Danio rerio
 TWF1ENSGALG00000009595Gallus gallus
 Twf1ENSMUSG00000022451Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TWF2 / Q6IBS0 / twinfilin actin binding protein 2ENSG0000024759663


Protein motifs (from Interpro)
Interpro ID Name
 IPR002108  Actin-depolymerising factor homology domain
 IPR028458  Twinfilin
 IPR029006  ADF-H/Gelsolin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0010613 positive regulation of cardiac muscle hypertrophy IEA
 biological_processGO:0030837 negative regulation of actin filament polymerization IEA
 biological_processGO:0042989 sequestering of actin monomers ISS
 biological_processGO:0043538 regulation of actin phosphorylation IDA
 biological_processGO:0051016 barbed-end actin filament capping IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005911 cell-cell junction IEA
 cellular_componentGO:0005925 focal adhesion HDA
 cellular_componentGO:0015629 actin cytoskeleton IEA
 cellular_componentGO:0030016 myofibril IEA
 cellular_componentGO:0030175 filopodium IEA
 cellular_componentGO:0032587 ruffle membrane IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0003785 actin monomer binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IDA
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding IEA
 molecular_functionGO:0045296 cadherin binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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