ENSG00000152583


Homo sapiens

Features
Gene ID: ENSG00000152583
  
Biological name :SPARCL1
  
Synonyms : Q14515 / SPARCL1 / SPARC like 1
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 4
Strand: -1
Band: q22.1
Gene start: 87473335
Gene end: 87531061
  
Corresponding Affymetrix probe sets: 200795_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000416971
Ensembl peptide - ENSP00000422903
Ensembl peptide - ENSP00000445678
Ensembl peptide - ENSP00000444832
Ensembl peptide - ENSP00000438188
Ensembl peptide - ENSP00000423483
Ensembl peptide - ENSP00000423448
Ensembl peptide - ENSP00000282470
Ensembl peptide - ENSP00000406251
Ensembl peptide - ENSP00000414856
NCBI entrez gene - 8404     See in Manteia.
OMIM - 606041
RefSeq - NM_001291976
RefSeq - NM_001291977
RefSeq - NM_004684
RefSeq - NM_001128310
RefSeq Peptide - NP_001278905
RefSeq Peptide - NP_001278906
RefSeq Peptide - NP_004675
RefSeq Peptide - NP_001121782
swissprot - E9PC64
swissprot - Q14515
swissprot - E7EU82
swissprot - D6RA29
swissprot - C9JJR8
swissprot - A0A024RDE1
swissprot - F5H1Y9
swissprot - F5H331
swissprot - F5H4Y3
Ensembl - ENSG00000152583
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sparcl1ENSDARG00000074989Danio rerio
 SPARCL1ENSGALG00000010929Gallus gallus
 P70663ENSMUSG00000029309Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SPARC / P09486 / secreted protein acidic and cysteine richENSG0000011314023


Protein motifs (from Interpro)
Interpro ID Name
 IPR001999  Osteonectin-like, conserved site
 IPR002048  EF-hand domain
 IPR002350  Kazal domain
 IPR003645  Follistatin-like, N-terminal
 IPR011992  EF-hand domain pair
 IPR015369  Follistatin/Osteonectin EGF domain
 IPR016359  SPARC-like protein 1
 IPR018247  EF-Hand 1, calcium-binding site
 IPR019577  SPARC/Testican, calcium-binding domain
 IPR036058  Kazal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0043687 post-translational protein modification TAS
 biological_processGO:0044267 cellular protein metabolic process TAS
 biological_processGO:0048856 anatomical structure development IBA
 cellular_componentGO:0005576 extracellular region IDA
 cellular_componentGO:0005615 extracellular space HDA
 cellular_componentGO:0005788 endoplasmic reticulum lumen TAS
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0005509 calcium ion binding IBA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005518 collagen binding IBA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0050840 extracellular matrix binding IBA


Pathways (from Reactome)
Pathway description
Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
Post-translational protein phosphorylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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